Results 161 to 170 of about 131,459 (309)

With the Rise of Right‐Wing Governments, Why a One‐Time “50% Health Tax” Will Be a Hard Sell and How It Could Be Implemented

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Recent calls from the World Health Organization (WHO) to globally impose a one‐time tax, labelled as “Health tax”, on tobacco, alcohol and sugar sweetened beverages (SSBs) aim to achieve a 50% retail price increase to reduce consumption and improve health outcomes.
Hazem Abbas   +6 more
wiley   +1 more source

CAnDE: Entity‐Based Relationship Exploration Using a Cards and Decks Metaphor

open access: yesComputer Graphics Forum, EarlyView.
We present CAnDE, a visual analytics approach for exploring dynamically defined entities in digital criminal data. Inspired by evidence boards, CAnDE uses a cards and decks metaphor that maps complex concepts to familiar interactions, including rotating, flipping and stacking cards.
K. A. Roggenbuck   +2 more
wiley   +1 more source

Directional information flow in human frataxin defines allosteric pathways connecting the hydrophobic core to the iron‐binding ridge

open access: yesThe FEBS Journal, EarlyView.
Human frataxin deficiency causes Friedreich's ataxia, yet how iron‐binding events are communicated across the protein is unclear. Using transfer entropy analysis of molecular dynamics simulations, we identify buried hydrophobic core leucines (LEU136, LEU140) as the source of directional signaling toward the iron‐binding acidic ridge.
Kevser Kübra Kırboğa   +1 more
wiley   +1 more source

Constrictions and shear stress are key determinants of amyloidogenic light chain (AL) amyloidosis

open access: yesThe FEBS Journal, EarlyView.
In this study, we investigate how flow constrictions and shear stress trigger cardiac antibody light chain (AL) fibril formation and deposition. We mimic the mechanical forces exerted by the heart and the microvasculature network using a mini‐peristaltic pump setup and a grid‐type microchannel network, respectively.
Yuji Goto   +11 more
wiley   +1 more source

Acoustic cell patterning reveals geometry- and substrate-dependent vasculogenesis and human embryo model development. [PDF]

open access: yesNat Commun
Xu Z   +11 more
europepmc   +1 more source

Hydrothermal origin of metabolic phosphorylation

open access: yesThe FEBS Journal, EarlyView.
Serpentinizing hydrothermal vents are candidate sites for biochemical origins. They generate extremely reducing conditions, depositing phosphite (HPO32−) and transition metals, including palladium, in the native (zero‐valent) state. Schlikker et al.
Manon L. Schlikker   +5 more
wiley   +1 more source

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