Results 121 to 130 of about 6,664,068 (391)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Building profile reconstruction using TerraSAR-X data time-series and tomographic techniques [PDF]

open access: yes, 2015
This work aims to show the potentialities of SAR Tomography (TomoSAR) techniques for the 3-D characterization (height, reflectivity, time stability) of built-up areas using data acquired by the satellite sensor TerraSAR-X.
Jean Marie, Nicolas   +2 more
core  

Sex Hormones in Acquired Immunity and Autoimmune Disease

open access: yesFrontiers in Immunology, 2018
Women have stronger immune responses to infections and vaccination than men. Paradoxically, the stronger immune response comes at a steep price, which is the high incidence of autoimmune diseases in women. The reasons why women have stronger immunity and
Vaishali R. Moulton
semanticscholar   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Acquired hemophilia A in a patient with advanced prostate cancer

open access: yesAutopsy and Case Reports, 2015
Acquired hemophilia A (AHA) is a rare disorder that results from the presence of autoantibodies against the clotting factor VIII (FVIII) causing hemorrhagic disorders.
Daniel da Motta Girardi   +6 more
doaj  

Genetic structure of community acquired methicillin-resistant Staphylococcus aureus USA300. [PDF]

open access: yes, 2012
BackgroundCommunity-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is a significant bacterial pathogen that poses considerable clinical and public health challenges.
Bansal, Vikas   +7 more
core   +2 more sources

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Acquired bronchoesophageal fistula

open access: yesLung India, 2009
Bronchoesophageal fistula in an adult is rarely encountered in clinical practice. Most commonly, they have malignant origin. We report a case of bronchoesophageal fistula secondary to trauma caused by upper gastrointestinal endoscopy.
Aggarwal Deepak   +2 more
doaj  

Acquired versus Non-Acquired Subsidiaries - Which Entry Mode do Parent Firms Prefer [PDF]

open access: yes
Despite the economic importance of international foreign direct investment (FDI) flows, investment decisions of multinational firms are not well understood.
Esther Kalkbrenner
core  

Acquired hemophilia A

open access: yesHematology, 2006
Acquired hemophilia A is a rare but severe autoimmune bleeding disorder, resulting from the presence of autoantibodies directed against clotting factor VIII. The etiology of the disorder remains obscure, although approximately half of all cases are associated with other underlying conditions.
openaire   +3 more sources

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