Results 171 to 180 of about 2,901,254 (317)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A collaborative approach to improve neurotrauma care and data collection – the GEO-TBI registry

Brain and Spine
Dr. Tommi Kalevi Korhonen, Mr Midhun Mohan, Mr David Clark, Ms Sara Venturini, Mr Michael Martin, Mr Angelos Kolias, Mr Alexis Joannides, Peter Hutchinson   +7 more
doaj   +1 more source

Case Report: Effect of setmelanotide treatment in a young patient with acquired hypothalamic obesity following <i>Escherichia coli</i> sepsis and meningoencephalitis with brain abscess. [PDF]

Front Endocrinol (Lausanne)
Dauleh H, Hussain K.
europepmc   +1 more source

Prognostic value of severity indicators of nursing-home-acquired pneumonia versus community-acquired pneumonia in elderly patients

, 2014
Motoi Ugajin, Kenichi Yamaki, Natsuko Hirasawa, Takanori Kobayashi, Takeo Yagi Department of Respiratory Medicine, Ichinomiya-Nishi Hospital, Ichinomiya City, Japan Background: The credibility of prognostic indicators in nursing-home-acquired pneumonia (
Hirasawa N, Kobayashi T, Yagi T, Yamaki K, Ugajin M   +4 more
core  

Development of transplant-acquired multiple food allergies: a case series

Organ transplantation is a life-saving procedure that is widely used in autoimmune diseases, malignancies and organ failures. However, it can bring many complications such as less known and newly described ones e.g. transplant-acquired food allergy (TAFA)
Ümmügülsüm Dikici, Öner Özdemir, Hacer Efnan Melek Arsoy   +2 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Ultrasound Features and Clinical Pathological Characteristics of Acquired Periungual Fibrokeratoma: Two Case Reports. [PDF]

Clin Cosmet Investig Dermatol
He D, Tao H, Xia H, Liu Z.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Pan-cancer analysis in the real-world setting uncovers immunogenomic drivers of acquired resistance post-immunotherapy. [PDF]

J Immunother Cancer
Keddar MR, Carrasco Pro S, Rabbie R, Kalender Atak Z, Muyas F, Stewart AC, Hammond SA, Palmer DC, Stewart R, Carey M, Burke K, Sidders B, Davies J, Dry JR, Martincorena I, Khosla S, Schoenfeld A, Miller ML.   +17 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source