Results 31 to 40 of about 2,901,254 (317)

Vitamin D, innate immunity and outcomes in community acquired pneumonia

open access: yes, 2011
We investigated the associations between vitamin D status, the antimicrobial peptides cathelicidin and beta defensin-2 and outcomes in community acquired pneumonia.
Karalus, Noel   +9 more
core   +1 more source

Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria. [PDF]

open access: yes, 2007
A recently proposed mechanism of protection for haemoglobin C (HbC; beta6Glu-->Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced ...
Warimwe, George M   +81 more
core   +1 more source

Genetic Determinism and the Innate-Acquired Distinction in Medicine

open access: yes, 2009
Kronfeldner M. Genetic Determinism and the Innate-Acquired Distinction in Medicine. Medicine Studies. 2009;1(2):167-181.This article illustrates in which sense genetic determinism is still part of the contemporary interactionist consensus in medicine ...
Maria E. Kronfeldner, Kronfeldner, Maria
core   +1 more source

Primary care summary of the British Thoracic Society Guidelines for the management of community acquired pneumonia in adults:2009 update. Endorsed by the Royal College of General Practitioners and the Primary Care Respiratory Society UK

open access: yes, 2010
The identification and management of adults presenting with pneumonia is a major challenge for primary care health professionals. This paper summarises the key recommendations of the British Thoracic Society (BTS) Guidelines for the management of ...
Woodhead, Mark A   +10 more
core   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Anthropometric measurements as a key diagnostic tool for familial partial lipodystrophy in women

open access: yesDiabetology & Metabolic Syndrome
Background Familial Partial Lipodystrophy (FPLD) is a disease with wide clinical and genetic variation, with seven different subtypes described. Until genetic testing becomes feasible in clinical practice, non-invasive tools are used to evaluate body ...
Victor Rezende Veras   +10 more
doaj   +1 more source

Differences in affinity of monoclonal and naturally acquired polyclonal antibodies against Plasmodium falciparum merozoite antigens [PDF]

open access: yes, 2015
Malaria is a major global cause of deaths and a vaccine is urgently needed.; We have employed the P. falciparum merozoite antigens MSP2-3D7/FC27 and AMA1, used them in ELISA, and coupled them in different ways using surface plasmon resonance (SPR) and ...
Stanisic, Danielle   +41 more
core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Calf skinfold measurements as a diagnostic tool for lipodystrophy syndromes: a cross-sectional study

open access: yesDiabetology & Metabolic Syndrome
Background Lipodystrophy syndromes (LS) are characterized by reduced body fat and associated metabolic complications, such as insulin resistance and diabetes. The diagnosis of LS can be challenging in clinical settings.
Grayce Ellen da Cruz Paiva Lima   +14 more
doaj   +1 more source

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