Results 111 to 120 of about 908,413 (222)

Atypical acquired hemophilia linked with primary biliary cholangitis: a unique case presentation

Future Science OA
Acquired hemophilia A is an uncommon disease often presented with bleeding episodes causing a significant mortality risk. The main responsible for the threatening hemorrhagic disorder is the Factor VIII autoantibody’s development.
Fatma Megdiche, Nour Siala, Faten Kallel, Imen Krichen, Hend Hachicha, Imen Frikha, Maha Charfi, Naourez Kallel, Moez Medhaffar, Hatem Masmoudi, Moez Elloumi, Choumous Kallel   +11 more
doaj   +1 more source

Safety of Lowering the Platelet Transfusion Threshold Before Central Venous Catheterisation in Patients With Haematological Diseases

European Journal of Haematology, Volume 117, Issue 6, Page 1531-1540, December 2026.
ABSTRACT Introduction Central venous catheter (CVC) insertion is frequently required in patients with haematological diseases. Despite limited evidence, thrombocytopenia often prompts prophylactic platelet transfusion before catheterisation. Methods We conducted an observational before‐and‐after study including the first non‐tunnelled CVC insertion ...
Mathias Lazarevic Lindblad, Elin Pålsson, Vladimir Lazarevic, Leila Naddi, Ola Borgquist, Lars Nilsson, Maria Adrian, Björn P. Bark, Thomas Kander   +8 more
wiley   +1 more source

FVIII hydrolysis mediated by anti-FVIII autoantibodies in acquired hemophilia

, 2008
International audienceAcquired hemophilia is a rare hemorrhagic disorder caused by the spontaneous appearance of inhibitory autoantibodies directed against endogenous coagulation factor VIII (FVIII).
Bayry, Jagadeesh, Borg, Jeanne-Yvonne, Dasgupta, Suryasarathi, Kaveri, Srinivas, Borel-Derlon, Annie, Wootla, Bharath, Dimitrov, Jordan, Lévesque, Hervé, Lacroix-Desmazes, Sébastien, Rao, Desirazu, Friboulet, Alain   +10 more
core   +1 more source

Advanced Molecular Analysis in Hemophilia A in a Single Step: Next Generation Sequencing (NGS) and Copy Number Variation (CNV) Analysis

International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1445-1454, December 2026.
ABSTRACT Background Hemophilia A, an X‐linked bleeding disorder caused by pathogenic variants in the F8 gene, requires precise genetic diagnosis for optimal management. Conventional stepwise sequence and copy number variation (CNV) analyses are time‐consuming and may leave some cases unresolved.
Enise Avci Durmusalioglu, Esra Isik, Basak Durmus Ozen, Mehmet Mert Topaloglu, Nihal Karadas, Kaan Kavakli, Melike Sezgin Evim, Tolga Aslan, Erşen Kavak, Adalet Meral Gunes, Funda Tayfun Kupesiz, Alphan Kupesiz, Fahri Sahin, Tahir Atik   +13 more
wiley   +1 more source

Hemophilia, HIV and AIDS : perspectives in living : workshop study guide / John (Jack) R. McDonald, Jonathan Cooper

, 1991
Prepared by the World Federation of Hemophilia in collaboration with the World Health Organization79 ...
World Health Organization, Copper, Jonathan, McDonald, John R, World Federation of Hemophilia   +3 more
core  

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1289-1297, December 2026.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

Concurrent congenital hemophilia B and acquired hemophilia A: a unique case report

Congenital hemophilia B is a rare X-linked recessive bleeding disorder caused by factor IX deficiency. Acquired hemophilia A is a rare, acquired bleeding disorder that presents with new-onset bleeding, especially in older adults, due to the development ...
Cirik, Salih, Bicim, Soykan, Berber, Ilhami, Kaya, Emin, Erkurt, Mehmet Ali, Hidayet, Emine, Kuku, Irfan   +6 more
core   +1 more source

Testing for Non‐Severe Heritable Platelet Function Disorders

International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1279-1288, December 2026.
ABSTRACT Heritable platelet function disorders (HPFD) are a diverse group of bleeding disorders characterised by a primary qualitative defect in platelet function rather than platelet number. HPFD may be broadly categorised according to the severity of bleeding, with Glanzmann thrombasthenia and Bernard Soulier syndrome classically considered severe ...
Kate Burley, Naomi Cornish, Maria Molina Carretero, Sarah K. Westbury   +3 more
wiley   +1 more source

Inhibitors against spontaneously acquired coagulation factors: Acquired hemophilia B [PDF]

, 2003
Los inhibidores adquiridos del factor IX son extremadamente raros. Un hombre de 70 años presentó sangrado profuso continuo luego de una cirugía ortopédica. Su PTT activado inicial fue 77.4 segundos (intervalo normal, 25-36) y su PT fue normal.
Sossa Melo, Claudia Lucía, Rodríguez, Pilar, Jiménez Sanguino, Sara Inés   +2 more
core  

Stratified Randomized Controlled Trial of ∅3.3 mm Versus ∅4.1 mm Hydrophilic Titanium‐Zirconium Implants Supporting Posterior Mandibular Fixed Prostheses in Hyperglycaemic Subjects

Clinical Oral Implants Research, Volume 37, Issue 11, Page 1328-1349, November 2026.
ABSTRACT Objective To compare ⌀3.3 mm and ⌀4.1 mm hydrophilic titanium‐zirconium implants supporting fixed dental prostheses (FDPs) in mandibular distal‐extension situations among participants with varying degrees of hyperglycaemia. Materials and Methods Participants were stratified according to HbA1c (5.8%–< 7.0% vs.
Supriya Ebenezer, Sreelakshmi Viswanath, Chitradevi Ramanathan, Alampalli V. Ramesh, Vinay V. Kumar   +4 more
wiley   +1 more source