Results 51 to 60 of about 908,413 (222)

Specific functional knee phenotypes are associated with increased osteoarthritis progression: A ≥10‐year longitudinal study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate osteoarthritis (OA) progression across functional knee phenotypes (FKPs) over a follow‐up period of ≥10 years. Methods This retrospective longitudinal study included 388 patients (764 knees) with healthy knees or early OA (Kellgren–Lawrence grade ≤1) at baseline and a minimum follow‐up of 10 years.
Sang Jun Song, Hyo Beom Lee, Cheol Hee Park   +2 more
wiley   +1 more source

Treatment of acquired factor VIII inhibitor with recombinant activated factor VIIa: data from the Italian registry of acquired hemophilia

Haematologica, 2004
We report on the data collected in the Italian Registry of acquired haemophilia (AH) in 2001. Recombinant activated factor VII (rFVIIa) was selected as first-line therapy in 19 bleeding episodes because of their severity and as salvage in one case ...
F Baudo, F de Cataldo, G Gaidano, Italian registry of acquired hemophilia   +3 more
doaj  

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Acquired Hemophilia during Pregnancy and Postpartum [PDF]

Hemophilia is a genetic disease that affects blood coagulation. Acquired hemophilia A is an autoimmune-mediated bleeding disorder in which antibodies against coagulation factor VIII develop.
Ruiz Reyes, Dionis, Águila Carbelo, Madyaret, Quiroga López, Ileana Beatriz, García Rodríguez, Diana, Herrero Díaz, Adriel   +4 more
core   +1 more source

Acquired Hemophilia A [PDF]

Hematology & Transfusion International Journal, 2017
Acquired hemophilia A AHA is a rare but potentially life threatening bleeding disorder caused by the development of auto antibodies against circulating factor VIII Age distribution is bimodal with a first peak occurring among young women in postpartum period and a second major peak among elderly patients Fifty percent of cases are idiopathic ...
openaire   +1 more source

A Rare Case of Acquired Haemophilia A Following Sigmoid Adenocarcinoma: Case Report and Literature Review

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Acquired haemophilia A (AHA) is a rare complication of malignancy. We report a case of AHA secondary to colorectal cancer which presented as post‐operative bleeding, progressive activated partial thromboplastin time prolongation, precipitous factor VIII (FVIII) decline and inhibitor development.
Benjamin Reardon, Harini Haran, Jennifer Curnow   +2 more
wiley   +1 more source

Whole genome sequencing of Sars-COV-2 from Covid-19 acquired hemophilia patient

, 2022
Acquired hemophilia is an atypical pathology of SARS-CoV-2 infection, which could be variant associated. Here, we share a sequence of SARS-CoV-2 genome from patient with Covid-19 acquired hemophilia.
Kamarudin, Norhidayah, Hussain, Mushtaq, Ibrahim, Ismail, Aslam, Ayesha, Zainulabid, Ummu Afeera, Periyasamy, Petrick, Ahmad, Hajar Fauzan   +6 more
core  

Acquired Factor VIII Inhibitors: Three Cases

Turkish Journal of Hematology, 2013
Acquired hemophilia A is a rare, but devastating bleeding disorder caused by spontaneous development of autoantibodies directed against coagulation factor VIII.
Tay Za Kyaw, S. Jayaranee, Ping Chong Bee, Edmund Fui Min Chin   +3 more
doaj   +1 more source

Acquired hemophilia

Haematologica, 1994
Acquired hemophilia is a very rare disease characterized by the presence of an autoantibody (mainly IgG) to factor VIII, with a clinical presentation resembling hemophilia A.
P Bouvry, P Recloux
doaj  

Postpartum Acquired Hemophilia A

Journal of Community Hospital Internal Medicine Perspectives
Acquired hemophilia A (AHA) is a bleeding disorder that occurs from aberrant production of autoantibodies that target factor VIII. The underlying cause of AHA is unclear but can present postpartum. Very few cases have reported instances of AHA coexisting with other hematological disorders, such as sickle cell trait (SCT).
Omar, Khawaja O., Sebastian, William, Kemper, Suzanne   +2 more
openaire   +2 more sources