Results 141 to 150 of about 118,635,816 (237)
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi +3 more
wiley +1 more source
Investigating the Distribution: Signal, Noise, and the Resolution Toolkit in Evidence‐Based Medicine
ABSTRACT Rationale, Aims and Objectives Evidence‐based medicine (EBM) manages observational noise but lacks an explicit framework for taxonomic blur: treatment‐relevant variation generated when syndromic populations mix patients differing in mechanism or treatment responsiveness. Patients present with syndromes, not resolved pathophysiological classes.
Frederick Arthur
wiley +1 more source
Cyclosporine treatment of acquired hemophilia due to factor VIII antibodies [PDF]
Acquired hemophilia, caused by autoantibodies against coagulation factor VIII, is usually treated with steroids, cyclophosphamide, intravenous gammaglobulins and sporadically other drugs.
Baele, Gaston +2 more
core
Postpartum Acquired Hemophilia
Miyahira, Takeshi +3 more
openaire +3 more sources
An Automated Microfluidic System for Haemostasis Assessment in Cirrhosis With Thrombocytopenia
ABSTRACT Background & Aims Conventional laboratory tests do not capture platelet–vessel wall interactions (primary haemostasis) occurring in vivo, limiting guidance before invasive procedures. This is relevant in patients with thrombocytopenia, hallmark of advanced cirrhosis. Microfluidic assays may overcome these limitations.
Niccolò Bitto +14 more
wiley +1 more source
Abstract Background Since the COVID‐19 pandemic, demand for blood products has remained high, while donations have declined. Institutional policies guiding the use of these products may affect their availability, utilisation and waste. We surveyed blood banks (BBs) in the United States (U.S.) to assess policies and practices related to cryoprecipitate ...
Chinelo P. Onyenekwu +3 more
wiley +1 more source
Hematoma, Hemarthrosis, and Hemotympanum: A Case Report of Acquired Hemophilia A. [PDF]
Wolff A, Dahlen I, Singavi A.
europepmc +1 more source
When A Fall Isn't Just a Fall: Delayed Diagnosis of Acquired Hemophilia A in a Nonagenarian Patient. [PDF]
Gobhil S, Khunger A, Kandoth Karerat P.
europepmc +1 more source

