Results 91 to 100 of about 185,841 (304)

UK recommendations for chimerism testing and monitoring following allogeneic haematopoietic stem cell transplantation (HSCT): Best practice consensus guidelines from the British Society for Blood and Marrow Transplant and Cellular Therapies (BSBMTCT), NHS England Genomic Laboratory Hub (GLH) Haematological Malignancies Working Group, UK Cancer Genetics Group (UKCGG) and the UK National External Quality Assessment Service for Leucocyte Immunophenotyping (UK NEQAS LI)

British Journal of Haematology, EarlyView.
Summary In allogeneic haematopoietic stem cell transplantation (HSCT), important clinical decisions depend upon assessment of chimerism, including immunosuppressant dosing and donor lymphocyte infusions (DLI), which in turn can have major impacts on disease control, graft‐versus‐host disease (GVHD), immunity and ultimately patient survival.
Andrew Clark, Hazel Clouston, Kanchan Rao, Najeem Folarin, Josu De la Fuente, Angela Hamblin, Eduardo Olavarria, Debbie Richardson, Polly Talley, Victoria Potter, Justin Loke, Terri McVeigh, John Snowden   +12 more
wiley   +1 more source

Neurofilament light chain as a marker of peripheral nerve damage in vasculitic neuropathy? A cross‐compartmental correlation analysis in patients undergoing nerve biopsy

Brain Pathology, EarlyView.
To assess neurofilament light chain (NfL) as a biomarker of peripheral nerve damage, we correlated serumNfL concentrations with histopathological parameters from matched sural nerve biopsies. SerumNfL levels correlated with markers of acute axonal degeneration, but not with parameters reflecting chronic axonal loss.
Simon Streit, Jenny Meinhardt, Niclas Gimber, John Kestenbach, Christin Siewert, Jan Schmoranzer, Christian Meisel, Klemens Ruprecht, Frank L. Heppner, Péter Körtvélyessy, Werner Stenzel   +10 more
wiley   +1 more source

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

British Journal of Pharmacology, EarlyView.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source

Pulmonary Delivery of TCR Bispecific Proteins via Mesenchymal Stem Cells Facilitates Efficient Clearance of Lung Cancers

Cancer Science, EarlyView.
This study examines the deployment of T‐cell receptor (TCR) bispecific proteins administered through mesenchymal stem cells (MSCs) as a therapeutic strategy for pulmonary carcinoma. Utilizing a humanized murine model, TCR bispecific proteins exhibited potent cytotoxicity against pulmonary carcinoma cell lines, with MSCs proficiently localizing to the ...
Teng Wei, Wen Cao, Qiangnu Zhang, E. Wu, Qineng Li, Lili Ren   +5 more
wiley   +1 more source

Expression of Ley antigen in human immunodeficiency virus-infected human T cell lines and in peripheral lymphocytes of patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC).

, 1988
Masakazu Adachi, Masanori Hayami, Nobuhito Kashiwagi, Toshihiko Mizuta, Y. Ohta, M. John Gill, David S. Matheson, Taiki Tamaoki, C. Shiozawa, Sen‐itiroh Hakomori   +9 more
openalex   +1 more source

Pulmonary pseudotumour due to Corynebacterium equi in a patient with the acquired immunodeficiency syndrome. [PDF]

, 1988
George A. Bishopric, M F D'Agay, Benoı̂t Schlemmer, E. Sarfati, C Brochériou   +4 more
openalex   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Prevalent myocarditis at necropsy in the acquired immunodeficiency syndrome

, 1988
David W. Anderson, Renu Virmani, Joseph Reilly, Timothy J. O’Leary, Robert E. Cunnion, Max Robinowitz, Abe M. Macher, Usha Punja, Siocgo T Villaflor, Joseph E. Parrillo, William C. Roberts   +10 more
openalex   +1 more source

Contributions of 2‐h post‐load glucose, fasting blood glucose and glycosylated haemoglobin elevations to the prevalence of diabetes and pre‐diabetes in adults: A systematic analysis of global data

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Some studies found that the association of fasting blood glucose (FPG) or glycosylated haemoglobin (HbA1c) elevation with diabetic complications was not statistically significant after controlling for the confounding caused by 2‐h post‐load glucose (2hPG) elevation.
Xue Xue, Jiaxuan Li, Wenxiao Zheng, Bingrui Zhang, Shuting Wang, Jiayue Zhang, Zuyao Yang   +6 more
wiley   +1 more source

Disseminated Histoplasmosis in a Patient With Acquired Immunodeficiency Syndrome in a Non-Endemic Region (California). [PDF]

J Med Cases, 2023
Phan AT, Bhagat A, Maknouni B, Masroor M, Hasan M.   +4 more
europepmc   +1 more source