Results 111 to 120 of about 192,697 (373)

The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated‐B Cells

open access: yesExploration, EarlyView.
Bcas2 recruits DHX15 and SRSF7 to form a protein complex for the splicing of CSR‐related mRNA at the 5' ss and 3' ss, generating two mature mRNA isoforms, which are ultimately translated into CSR‐related proteins. These CSR‐related proteins bind to DNA associated with antibodies, affecting the DSB repair of the relevant DNA after AID induction, thereby
Yu Chen   +29 more
wiley   +1 more source

Qualidade de vida de pessoas vivendo com o vírus e síndrome da imunodeficiência humana

open access: yesRev Rene, 2019
Objective to characterize the Brazilian scientific production on the quality of life of people living with human immunodeficiency virus/Acquired Immunodeficiency Syndrome.Methods bibliometric study with 20 dissertations and 18 theses available at the ...
Sergio Vital da Silva   +5 more
doaj   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

open access: yesGlobal Challenges, EarlyView.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze   +8 more
wiley   +1 more source

Fast Reliability-based Algorithm of Finding Minimum-weight Codewords for LDPC Codes [PDF]

open access: yesarXiv, 2007
Despite the NP hardness of acquiring minimum distance $d_m$ for linear codes theoretically, in this paper we propose one experimental method of finding minimum-weight codewords, the weight of which is equal to $d_m$ for LDPC codes. One existing syndrome decoding method, called serial belief propagation (BP) with ordered statistic decoding (OSD), is ...
arxiv  

The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes

open access: yesGlia, EarlyView.
Loss of FMRP impairs human and rat oligodendrocyte (OL) morphology in vitro. FMRP‐deficient OLs show impaired maturation when engrafted in hypomyelinated mice. Rat Fmr1 knockout OLs show a delay in myelin sheath formation in vivo. ABSTRACT The Fragile X Messenger Ribonucleoprotein (FMRP) is an RNA binding protein that regulates the translation of ...
Vidya Ramesh   +15 more
wiley   +1 more source

Human Immunodeficiency Virus Related Non-Hodgkin’s Lymphoma

open access: yesBlood and Lymphatic Cancer: Targets and Therapy, 2023
Tesfaye Gessese,1 Fikir Asrie,2 Zewudu Mulatie1 1Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia; 2Department of Hematology and Immunohematology, School of Biomedical and Laboratory ...
Gessese T, Asrie F, Mulatie Z
doaj  

Cold comfort for healthcare workers? Medico-ethical dilemmas facing a healthcare worker after occupational exposure to HIV

open access: yesSouth African Family Practice, 2011
Following exposure to the human immunodeficiency virus (HIV) it is advisable for the healthcare worker (HCW) to take postexposure prophylaxis. A prerequisite for this is the establishment of the HIV status of the HCW and the patient.
T.E. Madiba, C.L. Jack, Y.A. Vawda
doaj   +1 more source

Network Analyses and Nervous System Disorders [PDF]

open access: yesarXiv, 2017
Network analyses in nervous system disorders involves constructing and analyzing anatomical and functional brain networks from neuroimaging data to describe and predict the clinical syndromes that result from neuropathology. A network view of neurological disease and clinical syndromes facilitates accurate quantitative characterizations and ...
arxiv  

Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of GATA2 Deficiency

open access: yesHead &Neck, EarlyView.
ABSTRACT Background GATA2 deficiency is a rare genetic disorder associated with hematologic, infectious, and neoplastic complications. We report a case of a patient with GATA2 deficiency who developed aggressive squamous cell carcinoma (SCC) of the head and neck, an atypical manifestation of this condition.
Brejjette Aljabi   +3 more
wiley   +1 more source

Factors associated with the severity of COVID‐19 outcomes in people with neuromuscular diseases: Data from the International Neuromuscular COVID‐19 Registry

open access: yesEuropean Journal of Neurology, Volume 30, Issue 2, Page 399-412, February 2023., 2023
Abstract Background and purpose Clinical outcome information on patients with neuromuscular diseases (NMDs) who have been infected with SARS‐CoV‐2 is limited. The aim of this study was to determine factors associated with the severity of COVID‐19 outcomes in people with NMDs.
Chiara Pizzamiglio   +93 more
wiley   +1 more source

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