Results 141 to 150 of about 381,869 (399)
Human Cyclophilins—An Emerging Class of Drug Targets
Medicinal Research Reviews, EarlyView.ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Case management of persons with acquired immunodeficiency syndrome in San Francisco. [PDF]
, 1988 The acquired immunodeficiency syndrome (AIDS) epidemic represents a growing challenge for the health care system and for case management models applied to persons with AIDS.
Benjamin, AR, Lee, PR, Solkowitz, SN
core
Medicine Advances, EarlyView.This study found that cervical cancer does not significantly affect HIV viral load or systemic immune suppression in HIV‐positive women, most of whom were virally suppressed. However, age, cancer stage, and socio‐economic status were significantly associated with immunological markers, with older women and those with advanced disease showing poorer HIV
Thokozani Maluwa +3 more
wiley +1 more source
Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages. [PDF]
, 1987 Primary human monocyte-derived macrophages (MDM) were shown to have diminished deoxynucleoside kinase activities compared to T lymphoblasts, and a reduced ability to phosphorylate dideoxynucleosides with anti-human immunodeficiency virus (HIV) activity ...
Carson, DA, Kornbluth, RS, Richman, DD
core
Acquired immunodeficiency syndrome in Brazil.
Croatian medical journal, 2002 To describe the acquired immunodeficiency syndrome (AIDS) epidemic in Brazil and analyze the impact of federal government measures addressing the problem since its onset.Retrospective review of AIDS epidemic data from its onset in 1980 up to the last published data in June 2001.AIDS was first reported in Brazil in 1980. By 1988, all 27 Brazilian states
openaire +4 more sources
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Patients with large vestibular schwannomas (VS) are at higher risk for adverse outcomes following microsurgical resection. This study aims to identify clinical and radiographic factors that may be predictive of adverse outcomes. Study Design Retrospective chart review. Setting Academic tertiary care center.
Jason L. Steele +8 more
wiley +1 more source
UVB phototherapy of the pruritic papular eruption of the acquired immunodeficiency syndrome
, 1992 Rube J. Pardo +4 more
openalex +1 more source
Opsoclonus‐Myoclonus: Not Always Paraneoplastic
Movement Disorders Clinical Practice, EarlyView.
Fernanda Lustosa Cabral Gomez +4 more
wiley +1 more source
ChemistryOpen, EarlyView.The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges +15 more
wiley +1 more source