Results 231 to 240 of about 185,841 (304)

Assessment of Perceived HIV Vulnerability, Knowledge Regarding HIV Transmission, and Associated Sociodemographic Factors Among Urban Slum Dweller Adults in Bangladesh: A Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Human Immunodeficiency Virus (HIV) remains a major global health challenge, disproportionately impacting vulnerable populations in low‐resource settings. Urban slum dwellers, often living in overcrowded and resource‐limited conditions, are among the most vulnerable to HIV infection due to socioeconomic and structural ...
Abu Bakkar Siddique, Md Golam Morshed, Md. Amirul Haque, Mintia islam Austha, Md. Mehedy Hassan, Samia Sultana, Mukta Moni, Md Mehedi Hasan, Rehnuma Abdullah, Md. Kaium Hossain, Md. Tajuddin Sikder   +10 more
wiley   +1 more source

Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib

The Journal of Clinical Pharmacology, Volume 65, Issue 10, Page 1273-1285, October 2025.
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez, Zhao Yang, William Schelman, Thomas C. Marbury, Juan C. Rondon, William Smith, Xiaofei Zhou, Neeraj Gupta, Caly Chien   +8 more
wiley   +1 more source

Zidovudine treatment of psoriasis associated with acquired immunodeficiency syndrome

, 1990
Díez García F, Ma Luisa Lozano-Del Hoyo, Salvio Serrano   +2 more
openalex   +1 more source

Sarcopenia and Its Individual Traits Independently Predict Mortality in Patients on Dialysis: A Systematic Review and Meta‐Analysis

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Loss of muscle mass, muscle weakness and the combination of the two are commonly observed in patients on dialysis and may have a negative impact on their survival. In this systematic review and meta‐analysis (MA), we evaluated the consistency and strength of the association between mortality risk and the presence of low muscle mass ...
Alice Sabatino, Alessandro Guerra, Kenia Mara Baiocchi de Carvalho, Lilian Cuppari, Juan Jesus Carrero, Peter Stenvinkel, Bengt Lindholm, Carla Maria Avesani   +7 more
wiley   +1 more source

Prevalence and risk factors of hypertension and diabetes among persons living with HIV in Zambia: results of a national facility‐based cross‐sectional survey

Journal of the International AIDS Society, Volume 28, Issue 10, October 2025.
Abstract Introduction Despite growing evidence on the rising burden of non‐communicable diseases (NCDs) in sub‐Saharan Africa, the national prevalence of hypertension, prediabetes and diabetes among persons living with HIV (PLHIV) in Zambia is largely unknown.
Chomba Mandyata, Sivile Suilanji, Samuel Bosomprah, Paul Somwe, Cosmas Zyambo, Mwiche Musukuma, Aggrey Mweemba, Malizgani Paul Chavula, Chipefwe Sichilima, Phoebe Bwembya, Mpanji Siwingwa, Richard Chibale, Henry Phiri, Joseph Zulu, Halwindi Hikabasa, Wilbroad Mutale   +15 more
wiley   +1 more source

Guanine Nucleotide Exchange Factors and Small GTPases: Their Regulation and Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 10, October 2025.
This review comprehensively examines the regulatory mechanisms and physiological roles of guanine nucleotide exchange factors (GEFs) and their small GTPase substrates, highlighting their significance in cellular processes and disease pathogenesis.
Zexing Lin, Chujun Ni, Haiyang Jiang, Huan Yang, Liting Deng, Peizhao Liu, Xuanheng Li, Yilong Yu, Weijie Li, Runnan Wang, Bo Liao, Jiaqi Kang, Juanhan Liu, Xiuwen Wu, Jianan Ren, Yun Zhao   +15 more
wiley   +1 more source

Molecular and Cellular Mechanisms of Respiratory Syncytial Viral Infection: Its Implications for Prophylactic and Therapeutic Pharmaceuticals

MedComm, Volume 6, Issue 10, October 2025.
Respiratory syncytial virus (RSV) causes substantial global morbidity, particularly in infants and elderly populations. This review summarizes key viral pathogenesis mechanisms and highlights recent advances in both prophylactic (vaccines, antibodies) and therapeutic (antiviral agents) strategies against RSV.
Xiaowen Liang, Yue Yin, Yuanlong Lin, Shiman Chen, Qi Qian, Jing Yuan, Liuqing Yang, Yang Yang   +7 more
wiley   +1 more source

Design Strategies for Novel Lipid Nanoparticle for mRNA Vaccine and Therapeutics: Current Understandings and Future Perspectives

MedComm, Volume 6, Issue 10, October 2025.
This review summarizes strategies to optimize lipid nanoparticles (LNPs) for improved targeting, endosomal escape, and safety. It highlights mRNA design, alternative delivery systems, and recent therapeutic advances across infectious diseases, cancer, and drug applications.
Xiaochi Li, Junli Li, Jiazheng Wei, Weixin Du, Cheng Su, Xiaobin Shen, Aihua Zhao, Miao Xu   +7 more
wiley   +1 more source