Results 231 to 240 of about 279,854 (292)

Age‐Adjusted Charlson Comorbidities Index for Survival Prognosis in Laryngeal Squamous Cell Carcinoma Patients

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 101-111, February 2026.
ABSTRACT Objective This study aimed to explore the prognostic relevance of the age‐adjusted Charlson Comorbidity Index (ACCI) in laryngeal squamous cell carcinoma (LSCC) survival. Methods This retrospective analysis was conducted on the medical records of 367 LSCC patients admitted to the First Hospital of Shanxi Medical University, China, from January
Ze‐Hui Gao   +5 more
wiley   +1 more source

Rapamycin Exerts Its Geroprotective Effects in the Ageing Human Immune System by Enhancing Resilience Against DNA Damage

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Using in vitro DNA damage assays in human T cells, ex vivo profiling of aged immune subsets and a small placebo‐controlled in vivo study, authors show that low‐dose rapamycin, a potent life‐extending mTOR inhibitor, enhances resilience against DNA damage in the human immune system.
Loren Kell   +8 more
wiley   +1 more source

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami   +2 more
wiley   +1 more source

Access to Healthcare Services for the Deaf: A Scoping Review of Reviews

open access: yesHealth Expectations, Volume 29, Issue 1, February 2026.
ABSTRACT Background Cultural and linguistic minorities are at a higher risk of poorer health, poorer health outcomes, and poorer quality of care, in part due to a lack of access to healthcare services. Inequities in access to healthcare services have been found in several Deaf populations and are associated with poorer physical and mental health ...
Marie‐Mychèle Pratte   +3 more
wiley   +1 more source

WHO classification of skin tumours: key updates in the fifth edition

open access: yesHistopathology, Volume 88, Issue 3, Page 555-568, February 2026.
This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Gabrielle Goldman‐Lévy   +29 more
wiley   +1 more source

Catatonia and elevated mortality: A population‐wide cohort study with healthy, sibling, and schizophrenia spectrum controls

open access: yesPsychiatry and Clinical Neurosciences, Volume 80, Issue 2, Page 121-128, February 2026.
Aim To determine whether catatonia is associated with increased long‐term all‐cause and cause‐specific mortality. Methods Using Taiwan's National Health Insurance Database (2000–2022), we assembled a population‐based cohort of all adults (≥18 years) with catatonia and matched each to four controls without catatonia on sex and birthdate.
Chih‐Wei Hsu   +7 more
wiley   +1 more source

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