Results 281 to 290 of about 271,613 (400)

Heterogeneous treatment effects of GLP‐1RAs and SGLT2is on risk of Alzheimer's disease and related dementia in patients with type 2 diabetes: Insights from a real‐world target trial emulation

Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract INTRODUCTION This study assessed the heterogeneous treatment effects (HTEs) of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) on the risk of Alzheimer's disease and related dementias (ADRD). METHODS This target trial emulation study included adults (≥ 50 years) with type 2 diabetes (
Huilin Tang, William T. Donahoo, Steven T. DeKosky, Yao An Lee, Pareeta Kotecha, Mikael Svensson, Jiang Bian, Jingchuan Guo   +7 more
wiley   +1 more source

Human Herpesvirus‐6 Infectious Meningitis With Lymphadenitis in an Immunocompetent Adult

Brain and Behavior, Volume 15, Issue 6, June 2025.
Human Herpesvirus‐6 infectious meningitis with lymphadenitis in an immunocompetent adult. CSF: cerebrospinal fluid; NGS: next‐generation sequencing; HHV‐6: Human herpes virus‐6 ABSTRACT Purpose Human Herpesvirus 6 (HHV‐6) infections are primarily observed in immunocompromised individuals, such as those with acquired immunodeficiency syndrome or organ ...
Yu Xie, Chenrui Zhang, Mingchi Ma, Ziqian Yin, Liqian Chen, Yimiao Yang, Shuang Wu, Yuanteng Fan, Yan Xu, Dan He   +9 more
wiley   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, Volume 11, Issue 2, Page 89-104, June 2025.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

Adrenal Insufficiency in a Patient with Acquired Immunodeficiency Syndrome.

, 1994
Koichi Fujii, Isao Morimoto, Atsushi Wake, Yohsuke Okada, Nobuo Inokuchi, Osamu Ishida, Yoichiro Nakano, S. Oda, Sumiya Eto   +8 more
openalex   +2 more sources

Fibroblasts‐specific p16INK4a exacerbates inflammageing‐mediated post‐infarction ventricular remodelling through interacting with STAT3 to regulate NLRP3 transcription

Clinical and Translational Medicine, Volume 15, Issue 6, June 2025.
In ageing fibroblasts, p16INK4a concurrently enhanced STAT3 di‐methylation mediated by EZH2 and suppressed the assembly of Bmi‐1‐EZH2/BCL‐6 complexes at the NLRP3 promoter region. These dual regulatory actions synergistically upregulated STAT3‐dependent NLRP3 transcription, thereby exacerbating inflammageing‐driven ventricular remodelling following ...
Xin Gu, Yingqiang Du, Jin'ge Zhang, Jiyu Li, Haiyun Chen, Yujie Lin, Yue Wang, Chunli Zhang, Shiyu Lin, Nannan Hao, Chengyi Peng, Jiacheng Ge, Jin Liu, Yan Liang, Yongjie Zhang, Xiaoyan Wang, Fang Wang, Jianliang Jin   +17 more
wiley   +1 more source

Transcoronary study of biomarkers in patients with heart failure: Insights into intracardiac production

ESC Heart Failure, Volume 12, Issue 3, Page 1640-1651, June 2025.
Abstract Aims Biomarkers are pivotal in the management of heart failure (HF); however, their lack of cardiac specificity could limit clinical utility. This study aimed to investigate the transcoronary changes and intracardiac production of these biomarkers.
Jie Ren, Junhan Zhao, Shengwen Yang, Shuoyan An, Chi Cai, Jing Wang, Min Gu, Hongxia Niu, Shurong Li, Wei Hua, Beiyao Gao   +10 more
wiley   +1 more source

The acquired immunodeficiency syndrome (AIDS)

Acta Médica del Centro, 2010
Francisco Parrilla Arias
doaj  

Clinical Courses and Pathological Findings in Two Gay Male Patients with Acquired Immunodeficiency Syndrome infected in Japan

, 1990
S Takamizawa, Ken Kaito, Shoko Hori, Akio Kikuchi, Takashi Hashimoto, J. Shimada, Tohru Miyahara, K Jyo, S Ushigome, Takefumi Nikaido   +9 more
openalex   +2 more sources

The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes

Glia, Volume 73, Issue 6, Page 1203-1220, June 2025.
Main Points Loss of FMRP impairs human and rat oligodendrocyte (OL) morphology in vitro. FMRP‐deficient OLs show impaired maturation when engrafted in hypomyelinated mice. Rat Fmr1 knockout OLs show a delay in myelin sheath formation in vivo. ABSTRACT The Fragile X Messenger Ribonucleoprotein (FMRP) is an RNA binding protein that regulates the ...
Vidya Ramesh, Eleni Tsoukala, Ioanna Kougianou, Zrinko Kozic, Karen Burr, Biju Viswanath, David Hampton, David Story, Bharath Kumar Reddy, Rakhi Pal, Owen Dando, Peter C. Kind, Sumantra Chattarji, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Lida Zoupi   +15 more
wiley   +1 more source