Results 291 to 300 of about 286,389 (401)
A Mathematical Model for Allergic Reactions Induced by the Therapy of HIV
Mathematical Methods in the Applied Sciences, Volume 48, Issue 14, Page 13816-13838, 30 September 2025.ABSTRACT A new mathematical model for cell evolution in HIV is introduced and studied. Delay differential equations are used to capture the dynamics of immune system cells involved in allergies, as well as the evolution of HIV viruses, infected and uninfected CD4 +$$ {}^{+} $$ cells, and cytotoxic T‐lymphocytes, under specific antiretroviral therapy ...
Rawan Abdullah +3 more
wiley +1 more source
International Journal of Cancer, Volume 157, Issue 6, Page 1086-1093, 15 September 2025.What's new? About half of penile squamous cell carcinomas are causally associated with inflammatory conditions such as lichen sclerosus (LSc), but few large‐scale studies have assessed the risk of penile cancer in men with LSc. Here, the authors conducted a large nationwide study in Denmark to estimate the risk of penile and non‐penile cancer in men ...
Marianne Gardar Stærk +5 more
wiley +1 more source
Campbell Systematic Reviews, Volume 21, Issue 3, September 2025.ABSTRACT This is the protocol for a Campbell systematic review. The objectives are as follows. The proposed overview of reviews aims to: (1) aggregate and systematize findings from multiple overviews of reviews, and offer a broader understanding of the factors, both facilitators and barriers related to PrEP awareness, uptake, and adherence among MSM ...
Guilherme G. Pinheiro +2 more
wiley +1 more source
Zebrafish as a Versatile Model Organism: From Tanks to Treatment
MedComm – Future Medicine, Volume 4, Issue 3, September 2025.The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava +9 more
wiley +1 more source
MedComm – Oncology, Volume 4, Issue 3, September 2025.Immune checkpoints in tumor immunotherapy. Ligand binding to the receptor inhibits immune cell function, promotes tumor cell immune escape, and suppresses the immune response. The pathways of action are VISTA‐IGSF11, TIM‐3‐Ceacam1, CD47‐SIRPα, CTLA‐4‐CD80/CD86, PD‐L1‐PD‐1, MHC‐1‐LILRB, and CD24 ‐ Siglec ‐10. There are also other immune checkpoints such
Han Sun +10 more
wiley +1 more source
Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut +1 more
wiley +1 more source
Addiction, Volume 120, Issue 9, Page 1780-1789, September 2025.Abstract Aims To develop machine‐learning algorithms for predicting the risk of a hospitalization or emergency department (ED) visit for opioid use disorder (OUD) (i.e. OUD acute events) in Pennsylvania Medicaid enrollees in the Opioid Use Disorder Centers of Excellence (COE) program and to evaluate the fairness of model performance across racial ...
Lingshu Xue +6 more
wiley +1 more source