Results 291 to 300 of about 381,869 (399)

Importance and Potential of Rare Disease Research in Pediatric Rheumatology and Beyond: Pushing Frontiers

open access: yesACR Open Rheumatology, Volume 7, Issue 12, December 2025.
Although individually occurring in less than 1 in 2,000 people, cumulatively, more than 7,000 rare diseases affect approximately 6% of the population worldwide. Children and young people are disproportionally challenged in number and severity, which may be explained by the large proportion of genetic conditions among rare diseases (70%–80%). Indeed, an
Christian M. Hedrich
wiley   +1 more source

Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts

open access: yesAmerican Journal of Hematology, Volume 100, Issue 12, Page 2305-2319, December 2025.
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent   +27 more
wiley   +1 more source

Acute effects of lactate infusion on metabolism, AD biomarkers, and cognition: The LEAN study

open access: yesAlzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract BACKGROUND Impaired cerebral glucose metabolism is a hallmark of Alzheimer's disease (AD). Lactate is an alternative brain fuel; however, whole‐body lactate metabolism has not been measured in AD. METHODS The Lactate for Energy and Neurocognition Trial (NCT05207397) was a single‐arm trial that enrolled 24 cognitively healthy (CH) older adults ...
Riley E. Kemna   +12 more
wiley   +1 more source

Green Synthesis of Silver Nanoparticles: A Review of Polymer and Antimicrobial Drug Combinations for Enhanced Antimicrobial Applications

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Silver nanoparticles (AgNPs) synthesized using eco‐friendly green synthesis approaches exhibit remarkable antimicrobial activity and enhanced drug delivery potential. Polymer‐AgNPs conjugates further improve drug stability and targeted delivery, offering a multifunctional platform for biomedical applications.
Mukil Madhusudanan   +6 more
wiley   +1 more source

Hibiscus rosa‐sinensis: A Multifunctional Flower Bridging Nutrition, Medicine, and Molecular Therapeutics

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
H. rosa‐sinensis bioactives modulate oxidative and inflammatory pathways. Myricetin and rutin show strong α‐glucosidase and SOD binding affinity. Exhibits safe, multifunctional use in health, food and nutraceuticals. ABSTRACT Hibiscus rosa‐sinensis, commonly known as the shoe flower, thrives in tropical and subtropical regions across South China, Asia,
Hassan Raza   +6 more
wiley   +1 more source

Validation and modification of Triage Risk Screening Tool in risk stratification for older adults attending the emergency department

open access: yesHong Kong Journal of Emergency Medicine, Volume 32, Issue 6, December 2025.
Abstract Objective To assess the diagnostic accuracy of the triage risk screening tool (TRST) in a Hong Kong emergency department (ED) and explore additional predictors to enhance its performance. Methods This was a single center retrospective cohort study.
Wai Yin Leung   +3 more
wiley   +1 more source

Monocyte function in intravenous drug abusers with lymphadenopathy syndrome and in patients with acquired immunodeficiency syndrome: selective impairment of chemotaxis.

open access: green, 1985
Guido Poli   +8 more
openalex   +1 more source

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