Results 301 to 310 of about 197,747 (335)

Zidovudine treatment of psoriasis associated with acquired immunodeficiency syndrome

, 1990
Díez García F, Marina del Hoyo, Salvio Serrano   +2 more
openalex   +1 more source

Carbonic anhydrase‐9‐targeted near‐infrared photoimmunotherapy as a theranostic modality for clear cell renal cell carcinoma

International Journal of Cancer, Volume 156, Issue 12, Page 2377-2388, 15 June 2025.
What's New? The cell‐surface glycoprotein carbonic anhydrase‐9 (CA9) is highly expressed in clear cell renal cell carcinoma (ccRCC), suggesting that it may be leveraged as a therapeutic target. A promising and minimally invasive approach for CA9‐targeting is near‐infrared photoimmunotherapy (NIR‐PIT).
Hiroshi Fukushima, Seiichiro Takao, Aki Furusawa, Motofumi Suzuki, Youfeng Yang, Christopher J. Ricketts, Makoto Kano, Shuhei Okuyama, Hiroshi Yamamoto, Miyu Kano, Mark W. Ball, Peter L. Choyke, W. Marston Linehan, Hisataka Kobayashi   +13 more
wiley   +1 more source

Elucidating the Molecular Landscape of Cystic Kidney Disease: Old Friends, New Friends and Some Surprises

American Journal of Medical Genetics Part A, Volume 197, Issue 6, June 2025.
ABSTRACT Cystic kidney diseases (CyKD) are a diverse group of disorders affecting more than 1 in 1000 individuals. Over 120 genes are implicated, primarily encoding components of the primary cilium, transcription factors, and morphogens. Prognosis varies greatly by molecular diagnosis. Causal variants are not identified in 10%–60% of individuals due to
Deborah Watson, Frank Mentch, Jonathan Billings, Kayleigh Ostberg, Michael E. March, Jennifer M. Kalish, Dong Li, India Cannon, Lisa M. Guay‐Woodford, Erum Hartung, Alanna Strong   +10 more
wiley   +1 more source

Transcoronary study of biomarkers in patients with heart failure: Insights into intracardiac production

ESC Heart Failure, Volume 12, Issue 3, Page 1640-1651, June 2025.
Abstract Aims Biomarkers are pivotal in the management of heart failure (HF); however, their lack of cardiac specificity could limit clinical utility. This study aimed to investigate the transcoronary changes and intracardiac production of these biomarkers.
Jie Ren, Junhan Zhao, Shengwen Yang, Shuoyan An, Chi Cai, Jing Wang, Min Gu, Hongxia Niu, Shurong Li, Wei Hua, Beiyao Gao   +10 more
wiley   +1 more source

The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes

Glia, Volume 73, Issue 6, Page 1203-1220, June 2025.
Main Points Loss of FMRP impairs human and rat oligodendrocyte (OL) morphology in vitro. FMRP‐deficient OLs show impaired maturation when engrafted in hypomyelinated mice. Rat Fmr1 knockout OLs show a delay in myelin sheath formation in vivo. ABSTRACT The Fragile X Messenger Ribonucleoprotein (FMRP) is an RNA binding protein that regulates the ...
Vidya Ramesh, Eleni Tsoukala, Ioanna Kougianou, Zrinko Kozic, Karen Burr, Biju Viswanath, David Hampton, David Story, Bharath Kumar Reddy, Rakhi Pal, Owen Dando, Peter C. Kind, Sumantra Chattarji, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Lida Zoupi   +15 more
wiley   +1 more source

Preascitic Sodium Retention in Cirrhosis: A Role for Disregulated Proteolysis by Proprotein Convertases?

Liver International Communications, Volume 6, Issue 2, June 2025.
ABSTRACT Loss of effective arterial blood volume, secondary hyperaldosteronism, adrenergic activation and nonosmotic hypersecretion of vasopressin induce sodium and water retention in cirrhotic patients with ascites. The mechanisms of sodium retention that precede ascites formation remain elusive.
Giovanni Sansoè, Manuela Aragno, Florence Wong   +2 more
wiley   +1 more source

Improvement of the predictive value of CD4+ lymphocyte count by b2-microglobulin, immunoglobulin A and erythrocyte sedimentation rate [PDF]

, 1993
Bek, Barbara, Bogner, Johannes R., Burkowitz, Jörg, Koch, Judith, Koch, Meinrad A., Schwartländer, Bernhard, Skarabis, Horst   +6 more
core  

Soluble Thrombomodulin Is Associated With Endothelial Dysfunction Syndromes After Pediatric Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, Volume 72, Issue 6, June 2025.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (HSCT) is challenged by endothelial dysfunction‐related syndromes like sinusoidal obstruction syndrome (SOS), capillary leak syndrome (CLS), and severe acute graft‐versus‐host disease (aGvHD). We investigated soluble thrombomodulin (sTM), an endothelial damage marker, in relation to
Denise Elbæk Horan, Pär I. Johansson, Marianne Ifversen, Claus H. Nielsen, Klaus Müller, Katrine Kielsen   +5 more
wiley   +1 more source