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Acquired long QT syndrome in hospitalized patients
Heart Rhythm, 2017Acquired long QT syndrome (ALQTS) has long been overlooked in clinical practice. Recent studies reported that severe ALQTS (QTc ≥500 ms) in hospitalized patients is associated with increased all-cause mortality.The purpose of this study was to determine the role of ALQTS in the clinical outcomes of hospitalized patients.Electronic medical records were ...
Haixu Yu, Li Zhang, Ying Liu
exaly +3 more sources
Pharmacogenomics and Acquired Long QT Syndrome
Pharmacogenomics, 2005During the past decade pharmaceutical companies have been faced with the withdrawal of some of their marketed drugs because of rare, yet lethal, postmarketing reports associated with ventricular arrhythmias. The implicated drugs include antiarrhythmics, but also non-cardiac drugs, such as histamine blockers, antipsychotics, and antibiotics.
Aerssens, J.M.M.R., Paulussen, A.D.
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Pediatric Emergency Care, 2014
Acquired long QT syndrome (LQTS) is a disorder of cardiac repolarization most often due to specific drugs, hypokalemia, or hypomagnesemia that may precipitate torsade de pointes and cause sudden cardiac death. Common presentations of the LQTS are palpitations, presyncope, syncope, cardiac arrest, and seizures.
Marzuillo P. +5 more
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Acquired long QT syndrome (LQTS) is a disorder of cardiac repolarization most often due to specific drugs, hypokalemia, or hypomagnesemia that may precipitate torsade de pointes and cause sudden cardiac death. Common presentations of the LQTS are palpitations, presyncope, syncope, cardiac arrest, and seizures.
Marzuillo P. +5 more
openaire +4 more sources
Protective effect of acquired long QT syndrome in Takotsubo syndrome
Internal Medicine Journal, 2019AbstractBackgroundClinical variables that predict long‐term mortality and recurrence of Takotsubo syndrome (TTS) are not completely understood as the role of acquired corrected QT interval (QTc) prolongation.AimTo detect the prevalence of QTc interval prolongation in patients with TTS and to evaluate its long‐term prognostic impact.MethodsQTc intervals
Anna Hohneck +2 more
exaly +3 more sources
Ciprofloxacin-induced acquired long QT syndrome
Heart Rhythm, 2004Quinolone antibiotics have potentially serious proarrhythmic effects. The effects on intracardiac potassium channels result in QT interval prolongation, leading to torsades de pointes. Evidence suggests fluoroquinolones cause QT-mediated proarrhythmia, and weak evidence links ciprofloxacin with QT-mediated arrhythmias.
Manu, Prabhakar, Andrew D, Krahn
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Acquired long QT syndrome and torsade de pointes
PACE - Pacing and Clinical Electrophysiology, 2018AbstractSince its initial description by Jervell and Lange‐Nielsen in 1957, the congenital long QT syndrome (LQTS) has been the most investigated cardiac ion channelopathy. Although congenital LQTS continues to remain the domain of cardiologists, cardiac electrophysiologists, and specialized centers, the by far more frequent acquired drug‐induced LQTS ...
Nabil El-Sherif, Mohamed Boutjdir
exaly +3 more sources
Post-acute management of the acquired long QT syndrome
Postgraduate Medical Journal, 2014Abstract The mechanisms underlying drug induced QT prolongation and the immediate treatment of torsade de pointes have been extensively studied but the post-acute management of the Acquired Long QT Syndrome (ALQTS) remains to be addressed.
Sérgio, Barra +3 more
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Acquired long QT syndrome and elective anesthesia in children
Pediatric Anesthesia, 2006SummaryWe present the case of a child who had had a previous episode of torsades de pointes (TdP) and who was scheduled for elective surgery under general anesthesia. The pathophysiology of this condition and the anesthesia concerns are discussed. An 8‐year‐old male with a history of osteogenic sarcoma had undergone an uneventful limb salvage procedure
Timothy B, Curry +2 more
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