Results 121 to 130 of about 1,160,233 (174)
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Candidate Gene Mutation Analysis in Idiopathic Acquired Sideroblastic Anemia (Refractory Anemia With Ringed Sideroblasts)

Leukemia Research, 2007
For most cases of idiopathic acquired sideroblastic anemia (IASA), the molecular pathogenesis is unknown, despite the consistent morphological signature of abundant pathological ringed sideroblasts with their characteristic iron-engorged mitochondria.
Terra L Lasho
exaly   +3 more sources

Treatment of Acquired Sideroblastic Anemias

Hematology/Oncology Clinics of North America, 2020
Sideroblastic anemias are a heterogeneous group of disorders unified by the presence of abnormal erythroid precursors with perinuclear mitochondrial iron deposition in the bone marrow. Based on etiology, they are classified into clonal and nonclonal. Clonal sideroblastic anemias refer to myeloid neoplasms with ring sideroblasts (RS) and frequently have
Abhishek A, Mangaonkar   +1 more
openaire   +2 more sources

Philadelphia Chromosome in Idiopathic Acquired Sideroblastic Anemia

Acta Haematologica, 2009
In a 70-year-old female patient with idiopathic acquired sideroblastic anemia (IASA) the karyotype revealed the presence of a Philadelphia chromosome in one third of the bone marrow mitoses. The patient was followed for 45 months and no signs of chronic myeloid leukemia or other leukemic transformation developed.
A, Berrebi   +3 more
openaire   +2 more sources

Danazol Therapy in Acquired Idiopathic Sideroblastic Anemia

Acta Haematologica, 2009
Danazol, a synthetic androgen, was used in the treatment of 6 patients with acquired idiopathic sideroblastic anemia. No patient had a response to therapy as determined by an increase in either the hemoglobin or platelet count.
D C, Doll, Q S, Ringenberg, J W, Yarbro
openaire   +2 more sources

Primary acquired sideroblastic anemia, thrombocytosis, and trisomy 8

Annals of Hematology, 1997
Myelodysplastic syndromes are usually associated with pancytopenia. Disorders involving deletion of the long arm of chromosome 5 (5q-syndrome) and, rarely, patients with karyotypic abnormalities involving chromosome 3 associated with abnormal thrombopoiesis may have a normal or even raised platelet count.
K, Patel, P, Kelsey
openaire   +2 more sources

Combined Phenotypic and Genotypic Analysis of Ringed Sideroblasts in Acquired Idiopathic Sideroblastic Anemia

Acta Haematologica, 2009
Bone marrow from an 81-year-old male with acquired idiopathic sideroblastic anemia was found to be mosaic for 45, X/46, XY cell lines. Analysis of ringed sideroblasts for the presence or absence of a quinicrine fluorescent Y body indicated that all sideroblastic cells had lost the Y chromosome.
D D, Bennett, W S, Stanley, C B, Johnson
openaire   +2 more sources

Acquired idiopathic sideroblastic anemia: A new chromosomal abnormality

Cancer Genetics and Cytogenetics, 1983
We describe two patients with acquired idiopathic sideroblastic anemia and a terminal deletion of chromosome No. 11. In spite of the marked chromosomal abnormality neither patient has developed acute leukemia.
P, Schulman   +6 more
openaire   +2 more sources

Idiopathic acquired sideroblastic anemia terminating in acute myelosclerosis

Cancer, 1982
Acute myelosclerosis is an unusual myeloproliferative syndrome characterized by pancytopenia, absence of massive hepatosplenomegaly, and an absence of tear-drop poikilocytes. The marrow is usually fibrotic with atypical megakaryocytic and trilinear dyspoiesis. Median survival is approximately six months from onset of symptoms. The authors report a case
W M, Butler, H G, Taylor, U, Viswanathan
openaire   +2 more sources

Acquired Hemoglobin H in Refractory Sideroblastic Anemia

Archives of Internal Medicine, 1978
Two patients with idiopathic refractory sideroblastic anemia (IRSA) were found to have acquired hemoglobin H. Both developed leukemic syndromes. Six other patients with IRSA had normal hemoglobin electrophoretic patterns, and none has developed acute leukemia in up to five years. We suggest that hemoglobin electrophoresis be performed routinely in IRSA.
openaire   +1 more source

[Acquired idiopathic sideroblastic anemia (author's transl)].

La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1980
The authors consider the clinical and biological data of Acquired Idiopathic Sideroblastic Anemia (AISA). The physiopathology of the syndrome is discussed; the relationships between pathologic sideroblastosis, dyserythropoiesis and ferrokinetic modifications are pointed out.
F, Sigaux   +3 more
openaire   +2 more sources

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