Results 31 to 40 of about 1,160,233 (174)

Exploring the mechanistic link between SF3B1 mutation and ring sideroblast formation in myelodysplastic syndrome

Scientific Reports, 2022
Acquired sideroblastic anemia, characterized by bone marrow ring sideroblasts (RS), is predominantly associated with myelodysplastic syndrome (MDS). Although somatic mutations in splicing factor 3b subunit 1 (SF3B1), which is involved in the RNA splicing
Tetsuro Ochi, Tohru Fujiwara, Koya Ono, Chie Suzuki, Maika Nikaido, Daichi Inoue, Hiroki Kato, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Yukio Nakamura, Hideo Harigae   +13 more
doaj   +1 more source

ATP-Binding Cassette Transporter of Clinical Significance: Sideroblastic Anemia. [PDF]

J Pers Med
The ATP-binding cassette (ABC) transporters are a vast group of 48 membrane proteins, some of which are of notable physiological and clinical importance.
Ogunbileje JO, Harris N, Wynn T, Kashif R, Stover B, Osa-Andrews B.   +5 more
europepmc   +2 more sources

Sideroblastic anemia [PDF]

, 2016
Sideroblastic anemias are a heterogenous group of disorders that have as a common feature with the presence of ringed sideroblasts in the marrow. We present a case of young female, nursing student who presented with increasing palpitation, fatigue and ...
A Shrestha, P Bhandari, R Hamal
core   +1 more source

Central Nervous System Recurrence in a Patient Treated for Acute Promyelocytic Leukemia, Resulting in Sideroblastic Anemia: A Case Report

, 2022
BACKGROUND Previous cases that have been stated in this article have displayed that around 1% to 7% of patients that have been treated with chemotherapy for acute promyelocytic leukemia developed myelodysplastic syndrome or acute myeloid leukemia.
Morse, William J, Nawaz, Haroon, Choudhry, Ayesha   +2 more
core   +1 more source

SOD2 deficient erythroid cells up-regulate transferrin receptor and down-regulate mitochondrial biogenesis and metabolism.

PLoS ONE, 2011
BackgroundMice irradiated and reconstituted with hematopoietic cells lacking manganese superoxide dismutase (SOD2) show a persistent hemolytic anemia similar to human sideroblastic anemia (SA), including characteristic intra-mitochondrial iron deposition.
Florent M Martin, Xiuling Xu, Katharina von Löhneysen, Timothy J Gilmartin, Jeffrey S Friedman   +4 more
doaj   +1 more source

Zinc-Containing Over-The-Counter Product Causing Sideroblastic Anemia and Neutropenia. [PDF]

Cureus
Sideroblastic anemia is characterized by anemia, granulocytopenia, and bone marrow findings of vacuolated precursors and ringed sideroblasts. Zinc-induced copper deficiency can present as sideroblastic anemia and neutropenia.
Stagg MP, Miatech J, Majid B, Polala R.
europepmc   +2 more sources

Red Cell Distribution Width (RDW) as a Marker of Disease Activity in Patients with Hairy Cell Leukemia

Acta Medica, 1998
Red cell distribution width (RDW) was examined in 18 patients with hairy cell leukemia (HCL) treated with 2- chlorodeoxyadenosine (2-CdA), in 5 patients treated with Interferon alpha (IFN-alpha) and in 9 patients subjected to splenectomy.
Ladislav Chrobák, Pavel Žák, Karel Podzimek, Pravoslav Stránský   +3 more
doaj   +1 more source

The phenotypic spectrum of germline YARS2 variants:from isolated sideroblastic anemia to mitochondrial myopathy, lactic acidosis and sideroblastic anemia 2 [PDF]

, 2018
YARS2 variants have previously been described in patients with myopathy, lactic acidosis and sideroblastic anemia 2 (MLASA2). YARS2 encodes the mitochondrial tyrosyl-tRNA synthetase, which is responsible for conjugating tyrosine to its cognate mt-tRNA ...
Sieff, Colin A., Tamminga, Rienk, Campagna, DR, Alexander J. Rennings, Annet Simons, Swinkels, D.W., Huls, Gerwin A., Rudinger-Thirion, J, Hale, GA, Sieff, CA, Bottomley, Sylvia, Rienk Y. J. Tamminga, Farah, Roula, Tamminga, RYJ, Mayka Sanchez, Simons, Annet, Riley, Lisa, Arenillas, Leonor, Arenillas, L, Roodenburg, Richard J., Bottomley, SS, Dean R. Campagna, David P. Steensma, Arenillas Rocha, Leonor, Kaplan, Joel A., Janet L. Kwiatkowski, Campagna, Dean, Rodenburg, R.J., Heeney, MM, Frugier, Magali, Bechara, Elie, John Christodoulou, Richard J. Roodenburg, Ahmed, Rasha, Fleming, MD, Tamminga, Rienk Y.J., Kwiatkowski, JL, Mark D. Fleming, Kleefstra, Tjitske, Abboud, M, Fleming, Mark D., Roodenburg, Richard, Abboud, Miguel, Ahmed, R, Hilliard, Lee M., Joel A. Kaplan, Sieff, Colin, Kaplan, Joel, Kaplan, JA, Rudinger-Thirion, Joelle, Matthew M. Heeney, Schaap, Nicolaas, Riley, Lisa G., Swinkels, DW, Huls, Gerwin, Bechara, E, Heeney, Matthew, Abboud, Miguel Raul, Zhou, R, Christodoulou, John, Miguel Abboud, Hilliard, Lee, Roula Farah, Rennings, Alexander J., Campagna, Dean R., Fita-Torró, J, Josep Fita-Torró, Sanchez, Mayka, Schaap, N.P., Zhou, Ronghao, Steensma, David, Farah, R, Heeney, Matthew M., Riley, LG, Lisa G. Riley, Hale, Gregory A., Sánchez, M. J., Rasha Ahmed, Gregory A. Hale, Bechara, Elie A., Elie Bechara, Fita-Torro, Josep, Tjitske Kleefstra, Farah, Roula A., Rennings, Alexander, Bottomley, Sylvia S., Steensma, DP, Colin A. Sieff, Sanchez, M, Nicolaas Schaap, Rennings, Alexander Johannes Maria, Kleefstra, T, Joëlle Rudinger-Thirion, Roodenburg, RJ, Fleming, Mark, Frugier, M, Swinkels, Dorine W., Rennings, AJ, Magali Frugier, Swinkels, Dorine, Christodoulou, J, Huls, G, Leonor Arenillas, Tamminga, Rienk Y. J., Schaap, N, Kwiatkowski, Janet, Ronghao Zhou, Schaap, Nicolaas P.M., Simons, A., Simons, A, Sylvia S. Bottomley, Lee M. Hilliard, Hilliard, LM, Dorine W. Swinkels, Steensma, David P., Kleefstra, T., Gerwin Huls, Kwiatkowski, Janet L., Hale, Gregory, A.   +118 more
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SIDEROBLASTIC ANEMIA DIAGNOSIS AND MANAGEMENT

, 2018
Introduction: Sideroblastic anemia (SA), when defined 5 decades ago, was already recognized to occur in heterogeneous settings, including as familial or acquired disease.
Riyad Mohammed AlHajji , Nof Saadi Algarni , Jumanah Mohammad Bondagji , Hanan Bakhait Alghamdi , Salma Mosa Kamli , Asma Saad Al Ahmari , Ahmed Jameel Alyamani , Waleed Ali Althobaiti , Fatmah Mohsen Alhejji , Eidah Mohammed AL Ahmari , Abdullah Mohammed Alrajeh
core   +1 more source

Severe isoniazid related sideroblastic anemia [PDF]

, 2011
Isoniazid induced sideroblastic anemia is a rare event. We report case of a 45 year old Caucasian women with development of severe anaemia 4 month after introduction of Isoniazid as part of Tuberculosis treatment.
Kveti Kriz, Marie-Claire Desax, Rein Jan Piso   +2 more
core   +1 more source