From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
AortaSeg-60: an open real-world CT-angiography dataset of the aorta with automated segmentation masks and pathological variability. [PDF]
El Rahal D, Rotzinger DC, Fahrni G.
europepmc +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Erratum: "Is Social Media Use a Blessing or Cure for Motor Function and Skill Acquisition? An Opinion Paper". [PDF]
europepmc +1 more source
A System for Retrofitting Conventional MRI Systems for Simultaneous Multinuclear MRI/MRS. [PDF]
Hou J +4 more
europepmc +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Quantitative Multifrequency Ultrasound Imaging Using Narrowband Pulsing for Tissue Characterization. [PDF]
Hanson J, Wu C, Hoyt K.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Disrupting Motor Cortical Regional Activity during Motor Sequence Skill Training Impairs Human Motor Visuomotor Skill Acquisition and Learning That Is Not Sequence-Specific. [PDF]
Gutierrez I +4 more
europepmc +1 more source

