Results 111 to 120 of about 6,039,376 (329)
A Custom Solution for Acoustic Startle Response Setup with Spike2-Based Data Acquisition Interface [PDF]
, 2023 Arseniy Pelevin +3 more
openalex +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
AIROscope stellar acquisition [PDF]
The acquisition system which operates in conjunction with a balloon-borne TV system, boresighted to a telescope is described. It has two main functions, a star field monitor and an offset star tracker.
Deboo, G. J. +2 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The Design of Information Acquisition and Sharing [PDF]
, 2023 Dimitri Migrow, Francesco Squintani
openalex +1 more source
Modality effects in vocabulary acquisition
, 2019 It is unknown whether modality affects the efficiency with which humans learn novel word forms and their meanings, with previous studies reporting both written and auditory advantages.
Meyer, A. +3 more
core
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Data management for earth observations [PDF]
, 1977 The management of NASA earth observation data is discussed. User requirements are identified, as well as means to facilitate data acquisition. It is shown that LANDSAT data can be preprocessed to condense data into a more accessible format, thus reducing
Mcdonough, G. F.
core +1 more source