Results 191 to 200 of about 3,794,499 (287)

Multi-angle fluoroscopic lung perfusion imaging using x-ray pulsatility index: A pilot study in healthy subjects. [PDF]

Med Phys
Smith MR, Richmond BW, Gregory S, Cartwright M, Fouras A, Mogel GT, Hatt CR, Smith GT, Grice JV.   +8 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

S2V-DREME: a time-resolved slice-to-volume MR image reconstruction framework with dynamic reconstruction and motion estimation. [PDF]

Phys Med Biol
Qian X, Shao HC, Deng J, Dai Y, Zhang Y.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Association of Enlarged Perivascular Spaces and Total Small Vessel Disease Burden With Kidney Function. [PDF]

Neurology
Nash PS, Ambler G, Best JG, Wilson D, Du H, Al-Shahi Salman R, Jäger HR, Lip GYH, Goeldlin MB, Beyeler M, Bücke P, El-Koussy M, Mattle HP, Panos L, van Dam-Nolen DHK, Dubost F, Hendrikse J, Kooi ME, Mess WH, Nederkoorn PJ, Christ N, Bellut M, Gunkel S, Karayiannis CC, Ly J, Singhal S, Slater LA, Kim YD, Lee KJ, Lim JS, Hara H, Nishihara M, Tanaka J, Yoshikawa M, Demirelli DS, Tanriverdi Z, Uysal E, Coutts SB, Chappell FM, Makin SD, Fung Mak HK, Teo KC, Wong DYK, Hert L, Kubacka M, Lyrer PA, Polymeris AA, Wagner B, Zietz A, Abrigo J, Cheng C, Chu WC, Leung TW, Seiffge DJ, Fischer U, Jung S, Bos D, Fluri F, Phan TG, Srikanth VK, Heo JH, Bae HJ, Yakushiji Y, Orken DN, Smith EE, Wardlaw JM, Kai Lau GK, Engelter ST, Peters N, Soo YOY, Song TJ, Simister RJ, Wheeler DC, Werring DJ.   +73 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Dopamine D2/3 receptors and functional connectivity during fear extinction: A PET-fMRI study. [PDF]

Neuroimage Rep
Roy AA, Vegelius J, Björkstrand J, Lubberink M, Fredrikson M, Åhs F, Frick A.   +6 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

De Novo Facioscapulohumeral Muscular Dystrophy: A Severe Subtype Driven by D4Z4 Repeat Contractions. [PDF]

Neurol Genet
He Q, Lin X, Lin Y, Zheng Z, Zeng M, Zheng F, Chen X, Xu X, Liu B, Zhu S, Hong Y, Lin L, Lin X, Zheng Y, Qiu LL, Lin F, Wang N, Lin MT, Wang Z.   +18 more
europepmc   +1 more source