From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
ITO-Based Electrically Tunable Metasurface for Active Control of Light Transmission
NanomaterialsIn recent years, the rapid development of dynamically tunable metasurfaces has provided a new avenue for flexible control of optical properties.
Ruize Ma +4 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Collaboration Practices: An Analysis Within an Army Acquisition Program Office [PDF]
, 2014 Annual Acquisition Research SymposiumNaval Postgraduate School Naval Postgraduate School Acquisition Research ...
Blanton, Joseph R. +1 more
core +2 more sources
Volume II Acquisition Research Creating Synergy for Informed Change, Wednesday 18th Annual Acquisition Research Proceedings [PDF]
, 2021 Approved for public release; distribution is unlimited.Approved for public release; distribution is unlimited.Prepared for the Naval Postgraduate School, Monterey, CA 93943.Naval Postgraduate ...
Acquisition Research Program
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
An Analysis of the Defense Acquisition Strategy for Unmanned Systems [PDF]
, 2014 Annual Acquisition Research SymposiumWith impending budget reductions, there will be increasing pressure to narrow down on robotics technologies to achieve efficiencies and reduce costs.
Jones, Courtney D. +1 more
core +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Spoken Language Development and the Challenge of Skill Integration
Frontiers in Psychology, 2019 The development of phonological awareness, the knowledge of the structural combinatoriality of a language, has been widely investigated in relation to reading (dis)ability across languages.
Aude Noiray +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source