Results 51 to 60 of about 2,666,173 (266)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Remote Low-Coherence Fiber Vibrometer With Wide Dynamic Range
We present a remote low-coherence fiber vibrometer, which is composed of a hybrid configuration of Mach-Zehnder and Sagnac interferometer. In the interferometer, the signal and reference beams travel along the same path but in opposite directions.
Hui Li +4 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The availability of ZY-3 satellite data provides additional potential for surveying, mapping, and quantitative studies. Topographic correction, which eliminates the terrain effect caused by the topographic relief, is one of the fundamental steps in data ...
Ming-Liang Gao +5 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Optical bistability via an external control field in all-fiber ring cavity
We demonstrate a new scheme for realizing the Optical Bistability (OB) inside an all-fiber ring cavity with an external control field. In the absence of the external control field, the pump power is fixed below the threshold value of laser, and there is ...
Shili Li +4 more
doaj +1 more source
Monitoring the Etching Process of Hi-Bi Fiber Through a Fiber Loop Mirror
A method for monitoring the etching process of Hi-Bi fiber is proposed and demonstrated. The birefringence of the etching fiber is accurately calculated by tracking the shift of the interference spectrum in a high-birefringence fiber loop mirror ...
Danling Wu, Jun Zhu, Hui Wang, Benli Yu
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Salmonella screening is a key to ensure food safety in poultry supply chains. Currently available Salmonella detection methods including culture, polymerase chain reaction and enzyme-linked immuno-sorbent assay could not achieve rapid, sensitive, and in ...
Lei Wang +10 more
doaj +1 more source

