Results 91 to 100 of about 2,686,348 (267)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Missingness-aware prompting for modality-missing RGBT tracking

open access: yesJournal of King Saud University: Computer and Information Sciences
RGBT tracking has drawn great attention recently due to its ability to leverage enhancement and complementary information from the RGB and thermal infrared modalities.
Guyue Hu   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Dual Mach-Zehnder Interferometer Based on DCF and FCF for Temperature and Strain Measurement

open access: yesPhotonic Sensors
In this paper, a dual Mach-Zehnder interferometer for measuring both temperature and strain is proposed and verified by experiments. The sensor configuration involves cascading a four-core fiber and a double-clad fiber between two single-mode fibers.
Ya GAO   +4 more
doaj   +1 more source

Green Acquisitions

open access: yesEconomics Letters
Prior research suggests that investors value green firms at a premium. We add to this line of research and show that the acquirer’s cumulative abnormal return after the announcement of an acquisition is increasing in the ”greenness” of the target. We find tentative evidence suggesting that this pattern is more pronounced after the 2015 Paris agreement,
Andrea Schertler, Erik Theissen
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Mergers and Acquisitions

open access: yes, 2019
Abstract There are many types of mergers and acquisitions (M&A), be they a minority acquisition to explore a potential high growth emerging market, a takeover of a financially distressed firm with the aim of turning it around, or a private equity firm seeking short- to medium-term returns.
Pauliina Junni, Satu Teerikangas
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Acquisition of phonology [PDF]

open access: yes, 2000
An extended and revised version of this is also appeared in: L. Cheng & R.
openaire   +2 more sources

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