Results 71 to 80 of about 3,918,136 (283)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Poultry Science, 2020 Salmonella screening is a key to ensure food safety in poultry supply chains. Currently available Salmonella detection methods including culture, polymerase chain reaction and enzyme-linked immuno-sorbent assay could not achieve rapid, sensitive, and in ...
Lei Wang +10 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An Analysis of the Defense Acquisition Strategy for Unmanned Systems [PDF]
, 2014 Annual Acquisition Research SymposiumWith impending budget reductions, there will be increasing pressure to narrow down on robotics technologies to achieve efficiencies and reduce costs.
Jones, Courtney D. +1 more
core +2 more sources
The Proceedings of the 17th Annual Acquisition Research Symposium [PDF]
, 2020 Although this year’s symposium was not held as a live event, ARP continues the annual tradition of making publicly available papers and presentations from the many researchers in the ARP community who were scheduled to appear.
NPS Acquisition Research Program
core +2 more sources
IEEE Access, 2019 This study proposes a miniature and highly sensitive Fabry-Perot interferometer (FPI) based on aluminum - polyimide diaphragm integrated with a mass block for acceleration sensing. The composite diaphragms with a radius and thickness of 3.5 mm and 630 nm
Shili Li +5 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Li-GS: a fast 3D Gaussian reconstruction method assisted by LiDAR point clouds
Big Earth DataDigital twin technology, serving as a bridge between the physical and digital worlds, has demonstrated significant potential across various fields. In the domain of 3D reconstruction, recent advancements in Neural Radiance Fields (NeRF) and 3D Gaussian ...
Wenzhuo Chen +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source