Results 171 to 180 of about 6,039,376 (329)

Acquisitions: Drawings for Objects

The Rijksmuseum Bulletin, 2016
van der Hoorn, Esther, Baarsen, Reinier
openaire   +4 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Higher spatial resolution diffusion-weighted imaging improves characterization of white matter disconnection in Alzheimer's disease. [PDF]

Imaging Neurosci (Camb)
Merenstein JL, Song AW, Johnson KG, Whitson HE, Madden DJ.   +4 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Method for the Statistical Analysis of the Signals Generated by an Acquisition Card for Pulse Measurement [PDF]

Yaquelin Verenice Pantoja-Pacheco, Javier Yáñez-Mendiola   +1 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Patterns and Trajectories of Behavioral and Neuropsychiatric Symptoms in Frontotemporal Dementia and Primary Progressive Aphasia. [PDF]

Neurology
Marth L, Martinez-Murcia FJ, Górriz-Sáez JM, Denecke J, Ewers M, Prix C, Stockbauer AC, Bernhardt AM, Wagemann O, Wlasich E, Kustermann J, Peters O, Hellmann-Regen J, Droste Zu Senden L, Priller J, Spruth EJ, Spottke A, Asperger H, Schroeck F, Gamez A, Schneider A, Fliessbach K, Dinter E, Linn J, Günther R, Wiltfang J, Schott BH, Bähr M, Zerr I, Flöel A, Malinowski R, Buerger K, Janowitz D, Duzel E, Glanz W, Lüsebrink F, Teipel SJ, Kilimann I, Prudlo J, Hermann A, Synofzik M, Mengel D, Beichert L, Müller D, Petzold GC, Yakupov R, Hetzer S, Dechent P, Scheffler K, Schönecker S, Levin J.   +50 more
europepmc   +1 more source

AUTOMATED IMAGE ACQUISITION FOR REAL-TIME MOTION TRACKING DURING PROTON THERAPY

Hao Chen, Devin Miles, Kai Ding, Xiaoyu Hu, Curtiland Deville, Xun Jia, Heng Li   +6 more
openalex   +1 more source

Preconditioning tDCS facilitates subsequent tDCS effect on skill acquisition in older adults [PDF]

, 2016
Hakuei Fujiyama, Mark R. Hinder, Azadeh Barzideh, Charis Van de Vijver, Andreea Badache, Maria Nathalya Manrique-C, Paola Reißig, Xue Zhang, Oron Levin, Jeffery J. Summers, Stephan P. Swinnen   +10 more
openalex   +1 more source