Results 241 to 250 of about 6,039,376 (329)

Knowledge Acquisition of Power System Planning Based on Protocol Analysis

, 1988
S. Osaka, Ryoichi Fujiwara, Yoshiyuki Kohno, Asao Yamanishi   +3 more
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

The impact of generative AI health knowledge acquisition on adolescents' physical activity: the mediating role of exercise self-efficacy and the moderating effect of health information literacy. [PDF]

Front Public Health
Sun Q, Gou H, Xiang L, Hu C, Fang Y.
europepmc   +1 more source

185. Study on Artifacts Caused by 180° Data Acquisition in SPECT

, 1991
Morihiro Matsuda, Ryusei IWASAKI, Hironobu Yamashita, T Sanmiya, Shigehiko Kanaya, Takashi Kikegawa, Yasuhiro Ohba   +6 more
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Comparative accuracy of artificial intelligence versus manual interpretation in detecting pulmonary hypertension across chest imaging modalities: a diagnostic test accuracy meta-analysis. [PDF]

Front Artif Intell
Ahmed F, Haider F, Ali R, Arham M, Junaid Y, Dad A, Bakht K, Abbasi M, Malik BT, Mateen A, Gohar N, Ali R, Sattar Y, Ahmed M, Bakr M, Patel S, Almendral J, Alenezi F.   +17 more
europepmc   +1 more source

Online Data Acquisition and Reduction at the Magnetic Detector PLUTO

, 1976
G. Franke, R. Schmitz
openalex   +1 more source

EEOC v. NPMG Acquisition Sub, LLC [PDF]

, 2009
Bolton, Judge Susan R.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source