Results 141 to 150 of about 3,371,569 (315)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Reducing Costs and Increasing Productivity in Ship Maintenance Using Product Lifecycle Management, 3D Laser Scanning, and 3D Printing [PDF]
, 2014 Annual Acquisition Research SymposiumNaval Postgraduate School Naval Postgraduate School Acquisition Research ...
Naval Postgraduate School Acquisition Research Program +1 more
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Improving Defense Acquisition Decision Making [PDF]
, 2010 Symposium Presentation (for Acquisition Research Program)Approved for public release; distribution is unlimited.Naval Postgraduate School Acquisition Research ...
Fast, Bill
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Evolving Technologies in DoD Acquisition [PDF]
, 2007 Symposium Presentation (for Acquisition Research Program)Approved for public release; distribution is unlimited.Naval Postgraduate School Acquisition Research ...
Estep, Lorna B.
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Analysis of Trends From DOD-level Peer Reviewed Contracts [PDF]
, 2014 Annual Acquisition Research SymposiumNaval Postgraduate School Naval Postgraduate School Acquisition Research ...
Naval Postgraduate School Acquisition Research Program +1 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
From Push to Pull: Barriers to Marine Aviation Logistics Support Program II Modernization [PDF]
, 2014 Annual Acquisition Research SymposiumNaval Postgraduate School Naval Postgraduate School Acquisition Research ...
Beeson, James +2 more
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