Results 101 to 110 of about 3,819,731 (287)

A programmable fiber laser with full spatiotemporal reconfigurability [PDF]

open access: yesAPL Photonics
A structured light laser that enables on-demand generation of arbitrary optical field patterns and operates seamlessly across diverse lasing regimes constitutes a transformative platform, offering unprecedented flexibility in high-dimensional optical ...
Mengzhu Zhang   +7 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Missingness-aware prompting for modality-missing RGBT tracking

open access: yesJournal of King Saud University: Computer and Information Sciences
RGBT tracking has drawn great attention recently due to its ability to leverage enhancement and complementary information from the RGB and thermal infrared modalities.
Guyue Hu   +5 more
doaj   +1 more source

Green Acquisitions

open access: yesEconomics Letters
Prior research suggests that investors value green firms at a premium. We add to this line of research and show that the acquirer’s cumulative abnormal return after the announcement of an acquisition is increasing in the ”greenness” of the target. We find tentative evidence suggesting that this pattern is more pronounced after the 2015 Paris agreement,
Andrea Schertler, Erik Theissen
openaire   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Dual Mach-Zehnder Interferometer Based on DCF and FCF for Temperature and Strain Measurement

open access: yesPhotonic Sensors
In this paper, a dual Mach-Zehnder interferometer for measuring both temperature and strain is proposed and verified by experiments. The sensor configuration involves cascading a four-core fiber and a double-clad fiber between two single-mode fibers.
Ya GAO   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Requirements acquisition [PDF]

open access: yesSoftware Engineering Journal, 1996
Mildred L. G. Shaw, Brian R. Gaines
openaire   +2 more sources

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