Results 91 to 100 of about 3,794,499 (287)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Volume III Acquisition Research Creating Synergy for Informed Change, Thursday 18th Annual Acquisition Research Proceedings [PDF]
, 2021 Approved for public release; distribution is unlimited.Approved for public release; distribution is unlimited.Prepared for the Naval Postgraduate School, Monterey, CA 93943.Naval Postgraduate ...
Acquisition Research Program
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Remote Sensing, 2015 The complexity of the single linear hyperspectral pushbroom imaging based on a high altitude airship (HAA) without a three-axis stabilized platform is much more than that based on the spaceborne and airborne.
Aiwu Zhang +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Missingness-aware prompting for modality-missing RGBT tracking
Journal of King Saud University: Computer and Information SciencesRGBT tracking has drawn great attention recently due to its ability to leverage enhancement and complementary information from the RGB and thermal infrared modalities.
Guyue Hu +5 more
doaj +1 more source
Remote SensingWith the advancement of Earth observation technology and the improvement of multisource data acquisition capabilities, heterogeneous remote sensing image change detection technology has become increasingly important.
Hui Li +9 more
doaj +1 more source