Results 71 to 80 of about 1,016 (131)

WNK1 Kinase Activity Is Required for the Functional Maintenance of Podocyte Structure

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
The acute effects of WNK1 kinase inhibition on podocyte structure and function were determined at the level of: 1) renal function, by measurements of urinary protein and imaging of glomerular synaptopodin, 2) podocyte cell, by measurements and localization of actomyosin proteins and their regulators, and 3) focal adhesions at cell membrane extensions ...
Zhenan Liu, Eunyoung Lee, Shumeng Jiang, Joonho Yoon, Fouzia Ahmed, Mohammad A. Rahman, Philip Bleicher, Hani Y. Suleiman, Leslie A. Bruggeman, R. Tyler Miller, Audrey N. Chang   +10 more
wiley   +1 more source

Diagnostic yield of combined ACR TI-RADS and Sonoelastography in solid thyroid nodules in tertiary care center: A prospective cross-sectional Study

Journal of Karnali Academy of Health Sciences
Background: Thyroid nodules are prevalent, and accurate differentiation between benign and malignant nodules is crucial for management. We aim to evaluate the effectiveness of combining Thyroid Imaging Reporting and Data System (TIRADS) scoring with ...
Saubhagya Dhakal, Shailendra Katwal, Sharma Paudel, Birendra Kumar Yadav   +3 more
doaj   +3 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, Volume 600, Issue 3, Page 334-341, February 2026.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, Volume 600, Issue 4, Page 537-549, February 2026.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Correlation Between ACR TI-RADS and Bethesda System in Thyroid Nodules

Genel Tıp Dergisi
Abstract Background Thyroid nodules are frequently encountered in clinical practice Fine-needle aspiration (FNA) cytology is a reliable method to assess malignancy potential, though most nodules are benign. The American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) standardizes ultrasound evaluation, aiding malignancy ...
Emre Utkan Büyükceran, İsmail Dilek, Erbil Arık, Görkem Atasoy, Sezer Kula, Fatma Kaya, Sevcan Toraman, Murat Çalapkulu, Emre Can Çelebioğlu   +8 more
openaire   +1 more source

Biomarkers of microvascularture by ultra Micro-angiography (UMA) assist to identify papillary thyroid carcinoma (PTC) with atypia of undetermined significance

BMC Cancer
Background It is challenging to identify Papillary Thyroid Cancer (PTC) which shows atypia of undetermined significance (AUS) by Fine-needle Aspiration (FNA).
Qingsong Wang, Zhewei Li, Jie Zhang, Sijie Zhang, Lijun Wang, Hongjian Yao, Hong Zhang, Jing Li, Shuo Wang, Jinglai Sun, Wenhui Zhang, Hui Yu   +11 more
doaj   +1 more source

Rendimiento de las escalas ATA vs. ACR TI-RAD S en la valoración de riesgo de nódulos tiroideos

Revista Argentina de Radiología
Introducción: El estudio compara el rendimiento diagnóstico de dos escalas de riesgo para valorar el desenlace diagnóstico de cáncer de tiroides. Objetivo: Comparar el rendimiento de los sistemas de clasificación ATA y ACR TI-RADS en pacientes con ...
Felipe Rojas-Borda, Edgar Gonzales, Gina Saavera, Pamela Patiño   +3 more
doaj   +1 more source

Classifying thyroid nodules with the American College of Radiology Thyroid Imaging Reporting and Data System: A simple and cost-effective approach for assessing malignancy risk

Current Medicine Research and Practice
Background: Thyroid nodules are common, with up to 68% of adults having them. Ultrasonography is commonly used to examine them, but cannot determine if they are benign or malignant.
Pavani Muthoju, Rabiya Baseri Nelofar, Pravalya Chaparala   +2 more
doaj   +1 more source

ACR TI-RADS in a nutshell: A case report

International Journal of Radiology and Diagnostic Imaging, 2023
Dr. Dixit Varma, Dr. Ibrahim Khalil Ullah, Dr. Horish Rabha   +2 more
openaire   +1 more source

Performance of ACR TI-RADS and the Bethesda System in Predicting Risk of Malignancy in Thyroid Nodules at a Large Children's Hospital and a Comprehensive Review of the Pediatric Literature. [PDF]

Cancers (Basel), 2023
Hess JR, Van Tassel DC, Runyan CE, Morrison Z, Walsh AM, Schafernak KT.   +5 more
europepmc   +1 more source