Results 251 to 260 of about 621,752 (379)
Lithology and chemical analyses of core and cuttings from USGS drill hole near Gold Acres, Lander County, Nevada [PDF]
Chester T. Wrucke
openalex +1 more source
Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction
ABSTRACT Background Poor vascular health has been associated with age‐related declines in sensory functions, including olfaction. The current study was designed to test the hypothesis that cerebral small vessel disease underlies poor olfactory function due to structural declines in brain regions that support olfaction.
Mark A. Eckert+3 more
wiley +1 more source
To monitor small molecule‐induced changes in protein polyubiquitination in an unbiased manner, we employ enrichment through tandem ubiquitin binding entities coupled to LC‐MS/MS analysis (TUBE‐MS). By applying the workflow to PROTAC, p97‐ and deubiquitinase‐inhibitor treatment of cells, we demonstrate its broad applicability and reveal the induction of
Siska Führer+6 more
wiley +2 more sources
Spatial, temporal, and space-time analysis of leptospirosis cases in Acre, 2001-2022. [PDF]
Melchior LAK+3 more
europepmc +1 more source
Objective A growing body of evidence indicates a strong genetic overlap between developmental and epileptic encephalopathies (DEEs) and movement disorders. De novo loss‐of‐function variants in NUS1 have been recently identified in DEE cases. Herein, we report a large cohort of cases with pathogenic NUS1 variants and describe their clinical presentation
Sarah M. Brooker+79 more
wiley +1 more source
Molecular Survey of Hemopathogens in Bats from the Western Brazilian Amazon. [PDF]
Silva AID+11 more
europepmc +1 more source
Blood α‐Synuclein Separates Parkinson's Disease from Dementia with Lewy Bodies
Objective Aggregation of misfolded α‐synuclein (aSyn) within the brain is the pathologic hallmark of Lewy body diseases (LBDs), including Parkinson's disease (PD), and dementia with Lewy bodies (DLB) disease. Although evidence exists for aSyn “strains,” conformations with distinct biological properties, biomarkers for PD versus DLB are lacking.
George T. Kannarkat+17 more
wiley +1 more source