Results 31 to 40 of about 281 (139)
Darier disease: Current insights and challenges in pathogenesis and management. [PDF]
J Eur Acad Dermatol VenereolDarier disease (DD) is characterized by the following: Disrupted Ca2+ gradients, impaired desmosomes, impaired keratinocyte differentiation, type 17 inflammation, DC and LC ↓, Th17 cells ↑. DD treatment: First line: keratinocyte focused and/or anti‐inflammatory. Second line: experimental approaches like specific targeting of the inflammatory infiltrate.
Ettinger M +8 more
europepmc +2 more sources
The Skin in Cowden Syndrome [PDF]
, 2021 Cowden syndrome (CS) is an autosomal dominant condition caused by mutations in the phosphatase and tensin homolog (PTEN) gene, and is characterized by multiple hamartomas and a predisposition to malignant tumors.
Agnes Lim +3 more
core +1 more source
Dermoscopy of Inflammatory Dermatoses (Inflammoscopy) in Skin of Color—A Systematic Review by the International Dermoscopy Society “Imaging in Skin of Color” Task Force [PDF]
, 2023 Dermoscopic patterns of inflammatory dermatoses (inflammoscopy) have been extensively studied in the recent years, though data on patients with darker phototypes (IV-VI) are sparse.
Abhijeet Kumar Jha +20 more
core +2 more sources
Dermoscopy of acrokeratosis verruciformis of Hopf
Journal of the American Academy of Dermatology, 2017 Biswanath, Behera +5 more
openaire +4 more sources
An Uncommon Presentation of Darier-White Disease with Hystrix-like Palmoplantar Keratoderma [PDF]
, 2021 Darier-White disease is a relatively common autosomal dominant genodermatosis caused by mutation in the ATP2A2 gene. It is characterized by multiple warty papules coalescing into plaques in the seborrheic areas and by specific histological skin changes ...
Ellenbogen, Eran +6 more
core +3 more sources
Leukonychia: What Can White Nails Tell Us? [PDF]
, 2022 Changes in nail color can provide important clues of underlying systemic and skin disease. In particular, white discoloration (leukonychia) has a high prevalence with a wide array of potential relevant causes, from simple manicure habits to life ...
Iorizzo M, Pasch MC., Starace M
core +1 more source
Impaired Calcium Signalling and Neuropsychiatric Disorders in Darier Disease: An Exploratory Review [PDF]
, 2022 Darier (Darier-White) disease (DD) is an autosomal dominant skin disorder caused by pathogenic mutations in the ATP2 A 2 gene which encodes a calcium ATPase in the sarco-endoplasmic reticulum (SERCA2).
Ambur, Austin +3 more
core +2 more sources
Genodermatoses with behavioural sequelae [PDF]
, 2021 Children with genodermatoses are at an increased risk of developing behavioural disorders which may impart lasting damage on the individual and their family members.
Abbas, Ossama M. +5 more
core +1 more source
ACROKERATOSIS VERUCIFORMIS OF HOPF CLINICALLY MIMICKING AS NECROLYTIC ACRAL ERYTHEMA [PDF]
, 2022 Acrokeratosis verruciformis is very rare genodermatosis that was originally described by Hopf in 1931. A 29-years-old male presented to skin outpatient department with brown-colored hyperkeratotic plaques on dorsum of both feet that clinically mimicked ...
GARG, MONIKA +2 more
core +1 more source