Results 161 to 170 of about 2,314 (195)

Inhibition of amyloid β aggregation by acteoside, a phenylethanoid glycoside.

Bioscience, Biotechnology and Biochemistry, 2013
We examined the effects of acteoside (1a), which was isolated from Orobanche minor, and its derivatives on the aggregation of a 42-mer amyloid β protein (Aβ42) in our search for anti-amyloidogenic compounds for Alzheimer's disease (AD) therapy. Acteoside (1a) strongly inhibited the aggregation of Aβ42 in a dose-dependent manner.
Kazuhiro Irie, Hideyuki Shigemori, Hiroko Isoda   +2 more
exaly   +3 more sources

Acteoside and Acyl-Migrated Acteoside, Compounds in Chinese Kudingcha Tea, Inhibit α-Amylase In Vitro

Journal of Medicinal Food, 2017
Acteoside, the predominant polyphenol of small-leaved kudingcha, the Chinese tea, has various biological activities. In this study, we examined the acyl migration of acteoside to isoacteoside with high-temperature treatment of acteoside. The inhibitory effects of acyl-migrated acteoside and acteoside on α-amylase were investigated, as were their ...
Yuqin, Lu, Wenyu, Zhou, Yue, Feng, Yao, Li, Ke, Liu, Lizhong, Liu, Dongxu, Lin, Zhendan, He, Xuli, Wu   +8 more
openaire   +2 more sources

Biosynthesis of acteoside in cultured cells of Olea europaea

Journal of Natural Medicines, 2009
Five phenylethanoid glycosides (acteoside, isoacteoside, beta-oxoacteoside, beta-hydroxyacteoside, and salidroside) were isolated from a cell suspension culture of Olea europaea. We examined the biosynthesis of acteoside in olive cell cultures by using feeding experiments with stable isotope labeled precursors. The hydroxytyrosol moiety of acteoside is
Hiroshi, Saimaru, Yutaka, Orihara
openaire   +2 more sources

Natural P-gp inhibitor EGCG improves the acteoside absorption in Caco-2 cell monolayers and increases the oral bioavailability of acteoside in rats

Food and Chemical Toxicology, 2020
Acteoside is one of the most widespread phenylethanoid glycosides with pharmacological activities, including antioxidant, neuroprotective property, etc. However, its bioavailability is poor due to the low absorption and P-gp efflux. This study aimed to select food derived P-gp inhibitors for promoting the acteoside absorption and investigate whether ...
Jiyu Peng, Baiyi Lu, Tao Xu
exaly   +3 more sources

The distribution of acteoside among angiosperms

Biochemical Systematics and Ecology, 1992
Abstract The distribution of the phenylpropanoid glycoside acteoside is restricted to a constellation of families which may constitute a natural ordinal grouping. This distribution of acteoside contains many families traditionally clustered in a Scrophulariales-Lamiales complex.
openaire   +1 more source

Effect of rat intestinal flora in vitro on metabolites of acteoside

China Journal of Chinese Materia Medica, 2016
Acteoside was used for anaerobic incubation with rat intestinal flora in vitro. HPLC was used to detect the changes of acteoside at different incubation time points and HPLC-Q-TOF-MS was used to identify the metabolites of acteoside. The results showed that acteoside could be metabolized by rat intestinal flora in vitro and the metabolites were 3,4 ...
Wen-Xiu, Zhang, Biao, Yang, Yu-Mei, Hu, Zhao-Qing, Meng, Wen-Zhe, Huang, Zhen-Zhong, Wang, Wei, Xiao   +6 more
openaire   +2 more sources

Acteoside improves adipocyte browning by CDK6-mediated mTORC1-TFEB pathway

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2023
Adipocyte browning increases energy expenditure by thermogenesis, which has been considered a potential strategy against obesity and its related metabolic diseases. Phytochemicals derived from natural products with the ability to improve adipocyte thermogenesis have aroused extensive attention.
Yunxia, Sun, Xintao, Ni, Siyao, Cheng, Xiaofeng, Yu, Xiaoqin, Jin, Liangxin, Chen, Zhenggang, Yang, Daozong, Xia, Zhe, Chen, Miaofen G, Hu, Xiaoli, Hou   +10 more
openaire   +2 more sources

Metabolites of Dietary Acteoside: Profiles, Isolation, Identification, and Hepatoprotective Capacities

Journal of Agricultural and Food Chemistry, 2018
In recent years, cistanche tea has been increasingly used as a major herbal supplement in functional drinks, and it has attracted a growing number of consumers because of its excellent tonic effects and medicinal properties. Acteoside (ACT), which is the principal bioactive component of Chinese cistanche tea, possesses various pharmacological effects ...
Qingling Cui, Yingni Pan, Wei Zhang, Yanan Zhang, Shumeng Ren, Dongmei Wang, Zhenzhong Wang, Xiaoqiu Liu, Wei Xiao   +8 more
openaire   +2 more sources

The antiviral effects of acteoside and the underlying IFN-γ-inducing action

Food & Function, 2016
Acteoside, a natural phenylpropanoid glycoside from Kuding Tea, enhanced IFN-γ production in mouse lymphocytes in a dose-dependent manner, particularly in the CD4+ and CD8+ subsets of T lymphocytes.
Xun, Song, Jiang, He, Hong, Xu, Xiao-Peng, Hu, Xu-Li, Wu, Hai-Qiang, Wu, Li-Zhong, Liu, Cheng-Hui, Liao, Yong, Zeng, Yan, Li, Yue, Hao, Chen-Shu, Xu, Long, Fan, Jian, Zhang, Hong-Jie, Zhang, Zhen-Dan, He   +15 more
openaire   +2 more sources

ChemInform Abstract: Total Synthesis of the Phenylpropanoid Glycoside, Acteoside.

ChemInform, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Toshinari Kawada, Ryuji Asano, Shiho Hayashida, Tomoyasu Sakuno   +3 more
openaire   +1 more source