Results 1 to 10 of about 796,394 (251)

Three-Year Contraceptive Failure Rates During the HER Salt Lake Contraceptive Initiative.

JAMA Netw Open
Sanders JN, Carter G, Bullington BW, Gero A, Simmons R, Gawron LM, Kaiser JE, Turok DK.   +7 more
europepmc   +1 more source

The role of <i>trans</i>-acting factors in the pathogenesis of common psychiatric disorders. [PDF]

Epigenetics
Peedicayil J, Grayson DR.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Analysis of a Two-Stage Magnetic Precession Gear Exploiting 3D Finite Element Method. [PDF]

Materials (Basel)
Macyszyn L, Jedryczka C, Mysinski M.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Genome-Wide Identification, Expression Analysis of <i>HSF</i> Gene Family in Lanzhou Lily (<i>Lilium davidii</i> var. <i>unicolor</i>) and Screening of Key Genes <i>LdHSF10</i> and <i>LdHSF40</i> in Response to High-Temperature Stress. [PDF]

Plants (Basel)
Yao Q, Mi M, Xu C, Guo Q, Tao X, Fan T, Wu Z, Dang R, Zhao M, Yang Y, Ma H, Wei J.   +11 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Universal Free Contraception Coverage Policy, Out-of-Pocket Payments, and Costs.

JAMA Health Forum
Nethery E, Law MR, Cheng L, Bryan S, Clement F, Nickel NC, Norman WV, Black A, Helmer-Smith M, McGrail KM, Schummers L.   +10 more
europepmc   +1 more source

The relationship between role stress and compassion fatigue of medical workers: the mediating role of emotional labor and the moderating role of positive psychological capital. [PDF]

BMC Psychol
He T, Hou Y.
europepmc   +1 more source