Results 211 to 220 of about 12,313,442 (291)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Current practices and challenges in the management of acute bacterial skin and skin structure infections (ABSSSI): results from an Italian multicentre survey with expert discussion. [PDF]

JAC Antimicrob Resist
Gazzola L, Augello M, Cavinato S, Briozzo A, D'Amico F, Schiano Moriello N, Segala FV, Frallonardo L, Di Gennaro F, Saracino A, Tacconi D, Gilio M, Frontuto M, Parruti G, Cattelan A, Marchetti G.   +15 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

The relationship between role stress and compassion fatigue of medical workers: the mediating role of emotional labor and the moderating role of positive psychological capital. [PDF]

BMC Psychol
He T, Hou Y.
europepmc   +1 more source

Analysis of a Two-Stage Magnetic Precession Gear Exploiting 3D Finite Element Method. [PDF]

Materials (Basel)
Macyszyn L, Jedryczka C, Mysinski M.
europepmc   +1 more source

"We Are One of the Most Depressed Professionals": Nurses' Experiences of Psychological Hazards in A District Hospital. [PDF]

Nurs Open
Kodom PNB, Parimah F, Agyemang CB.
europepmc   +1 more source

Safety analysis of long-acting dual bronchodilator after market approval: a real-world study from FDA Adverse Event Reporting System (FAERS) database. [PDF]

J Thorac Dis
Gao S, Zhuang W, Song Q, Yan D, Chen L, Lai Z, Cheng Y, Yang X, Hu S.   +8 more
europepmc   +1 more source

Trends in HIV Viral Suppression in the POP-UP Low-Barrier Care Program for People With HIV Experiencing Homelessness or Unstable Housing. [PDF]

Open Forum Infect Dis
Imbert E, Fleming L, Oskarsson J, Cullen C, Shiels M, Friend J, Jackson J, Felten L, Zahedikia N, Montgomery F, Santos L, Mayorga-Munoz F, Rodriguez Y, Breganza Y, Grochowski J, Cohen J, Appa A, Koester K, Erguera X, Charlebois E, Gandhi M, Havlir DV, Christopoulos K, Hickey MD.   +23 more
europepmc   +1 more source

[ACTINg out].

Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008
openaire   +1 more source