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Current therapies for actinic keratosis

open access: yesInternational Journal of Dermatology, 2020
AbstractActinic keratosis (AK) is a very common skin disease caused by chronic sun damage, which in 75% of cases arises on chronically sun‐exposed areas, such as face, scalp, neck, hands, and forearms. AKs must be considered an early squamous cell carcinoma (SCC) for their probable progression into invasive SCC.
Caterina Dianzani   +2 more
exaly   +6 more sources
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Pharmacotherapy of actinic keratosis

Expert Opinion on Pharmacotherapy, 2009
Actinic keratosis (AK) represents the initial intraepidermal manifestation of abnormal keratinocyte proliferation with the potential of progression to squamous cell carcinoma (SCC). When in limited numbers, clinically visible AKs are treated individually with ablative and/or surgical procedures (lesion-directed treatment), while multiple and sublinical
Whitney Valins   +3 more
openaire   +3 more sources

Hypertrophic actinic keratosis

Journal of the American Academy of Dermatology, 1982
A common hypertrophic variant of actinic keratosis is presented. Bland cytologic features are dominant, and the pattern varies markedly from that of other actinic keratoses. Histologic and topographic evidence suggests that the hypertrophic changes are induced by the trauma of chronic rubbing.
Retna A. Billano, Walter P. Little
openaire   +3 more sources

PROLIFERATIVE ACTINIC KERATOSIS

International Journal of Dermatology, 1994
Abstract Background. Solar/actìnic keratoses (AKS) are premalignant lesions, usually less than 1 cm in diameter, that appear on chronically sun‐damaged skin. Methods. We describe four patients with a form of AK that enlarged and recurred despite standard treatment.
Aaron K. Joseph   +2 more
openaire   +3 more sources

Dermoscopic features of actinic keratosis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2007
SummaryActinic keratosis (AK) is a keratinocytic neoplasm that typically develops on sun‐damaged skin of elderly individuals. Only a few reports so far have described the dermoscopic diagnostic features of AK, mainly focusing on facial non‐pigmented AKs.
Peris K   +3 more
openaire   +5 more sources

Actinic Keratosis and Telangiectasia

Archives of Dermatology, 1972
To the Editor.— I recently saw a 60-year-old patient with rufous complexion who was covered with actinic keratosis and telangiectasia about his face, neck, and upper part of his chest. The history included a number of years of arsenic medication in 1936 for the treatment of amebiasis and radioactive thorium to his face in 1962 for actinic keratosis ...
openaire   +3 more sources

TREATMENT OF ACTINIC KERATOSIS

Archives of Dermatology, 1970
To the Editor.— It is well known that patients who use fluorouracil topically may get an intensification of the reaction when they are exposed to sunlight. To take advantage of this, a series of 100 patients were given an erythema dose of ultraviolet light to the right half of the face on the day prior to using topical 1% fluorouracil in Propylene ...
openaire   +3 more sources

Tenascin expression in actinic keratosis

Journal of Cutaneous Pathology, 2006
Background:  Tenascin is an extracellular matrix protein frequently expressed around neoplastic and non‐neoplastic lesions of the skin. Actinic keratoses (AKs) are intraepidermal neoplastic lesions of the sun‐exposed skin. They are classified according to the extension of dysplasia in four stages; they also present different histological varieties ...
Lentini, Maria   +3 more
openaire   +4 more sources

Pharmacotherapy of actinic keratosis: an update

Expert Opinion on Pharmacotherapy, 2012
Actinic keratosis (AK) represents the initial intraepidermal manifestation of abnormal keratinocyte proliferation, with the potential of progression to squamous cell carcinoma (SCC). Few visible AKs lead to the use of lesion-directed treatments, including ablative and/or surgical procedures.
Sadegh Amini, Brian Berman
openaire   +3 more sources

Actinic Keratosis

2014
In some respects actinic keratosis is the most common and best-known pathology in dermatology. Being such an ordinary pathology, actinic keratosis gives nevertheless insight into an extraordinary number of important biological and clinical processes. Actinic keratoses are found in significant numbers on the sun-exposed skin of Caucasians, especially ...
openaire   +3 more sources

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