Results 31 to 40 of about 70,210 (261)
Journal of Mazandaran University of Medical Sciences, 2020 Over recent years, nosocomial infections, and the morbidity and mortality associated with pathogenic bacteria have dramatically increased due to antibiotic resistance and imposed significant burdens on the global health system.
Yaser Delbari +4 more
doaj
Bioactivity Assessment of Indian Origin—Mangrove Actinobacteria against Candida albicans
Marine Drugs, 2018 Actinobacteria is found to have a potent metabolic activity against pathogens. The present study reveals the assessment of potent antifungal secondary metabolites from actinobacteria isolated from Indian marine mangrove sediments.
J. G. S. Pavan Kumar +3 more
doaj +1 more source
Microorganisms, 2020 Streptomyces are among the most promising genera in terms of production ability to biosynthesize a variety of bioactive secondary metabolites with pharmaceutical interest.
Nabila Mohammed Ishaque +10 more
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2021 Background and Objectives: Actinobacteria efficiently can produce different nanoparticles with various biological properties due to their ability to produce secondary metabolites.
Faezeh kabiri +4 more
doaj
Advanced Science, EarlyView.Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin +13 more
wiley +1 more source
Bioprospecting Deep-Sea Actinobacteria for Novel Anti-infective Natural Products
Frontiers in Microbiology, 2018 The global prevalence of drug resistance has created an urgent need for the discovery of novel anti-infective drugs. The major source of antibiotics in current clinical practice is terrestrial actinobacteria; the less-exploited deep-sea actinobacteria ...
Dongbo Xu +12 more
doaj +1 more source
Streptomyces, Greek Habitats and Novel Pharmaceuticals: A Promising Challenge
Microbiology Research, 2021 Bacteria of the genus Streptomyces produce a very large number of secondary metabolites, many of which are of vital importance to modern medicine. There is great interest in the discovery of novel pharmaceutical compounds derived from strepomycetes ...
Paris Laskaris, Amalia D. Karagouni
doaj +1 more source
Advanced Science, EarlyView.Furrow tillage resolves the conventional‐vs.‐no‐tillage trade‐off by simultaneously cutting CO2 efflux to 2.0–3.0 g C m−2 d−1 and unlocking high nutrient availability for the rice rhizosphere. This scalable agronomic solution strengthens soil health, enhances plant physiology, reshapes microbial metabolism, and shifts paddy systems toward a net ...
Arnab Majumdar +10 more
wiley +1 more source
Advanced Science, EarlyView.Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source