Metabolites, 2022 Anti-virulence agents are non-bacteriostatic and non-bactericidal emerging therapeutic options which hamper the production of virulence factors in pathogenic flora.
Yasuhiro Igarashi +2 more
exaly +4 more sources
Frontiers in Microbiology, 2015 Recent metagenomic studies have revealed that microbial diversity in the atmosphere rivals that of surface environments. This indicates that the atmosphere may be worth bioprospecting in for novel microorganisms, especially those selected for by harsh ...
Carolyn F Weber
exaly +4 more sources
A phylogenomic analysis of the
BMC Genomics, 2007 Background The genome of Mycobacterium tuberculosis harbors four copies of a cluster of genes termed mce operons. Despite extensive research that has demonstrated the importance of these operons on infection outcome, their physiological function remains ...
Riley Lee W, Casali Nicola
doaj +4 more sources
The Beneficial Effects of Actinomycetales Immune Modulators in the Pancreas of Diabetic Rats [PDF]
Advanced Pharmaceutical Bulletin, 2021 Purpose: Type 1 diabetes mellitus (T1DM) has dramatically increased in recent years, especially in young people, and limits the life quality of the patients involved.
Monireh Khordadmehr +6 more
doaj +2 more sources
A Novel Lineage of Endosymbiotic Actinomycetales: Genome Reduction and Acquisition of New Functions in Bifidobacteriaceae Associated With Termite Gut Flagellates. [PDF]
Environ MicrobiolCellulolytic flagellates are essential for the symbiotic digestion of lignocellulose in the gut of lower termites. Most species are associated with host‐specific consortia of bacterial symbionts from various phyla.
Silva JK +4 more
europepmc +2 more sources
Bioactivities and Extract Dereplication of Actinomycetales Isolated From Marine Sponges
Frontiers in Microbiology, 2019 In the beginning of the twenty-first century, humanity faces great challenges regarding diseases and health-related quality of life. A drastic rise in bacterial antibiotic resistance, in the number of cancer patients, in the obesity epidemics and in ...
José D. Santos +15 more
doaj +2 more sources
F420H2-dependent degradation of aflatoxin and other furanocoumarins is widespread throughout the actinomycetales. [PDF]
PLoS ONE, 2012 Two classes of F(420)-dependent reductases (FDR-A and FDR-B) that can reduce aflatoxins and thereby degrade them have previously been isolated from Mycobacterium smegmatis. One class, the FDR-A enzymes, has up to 100 times more activity than the other. F(
Gauri V Lapalikar +5 more
doaj +2 more sources
Gut microbiota may affect Alzheimer's disease through synaptic function mediated by CAMs pathway: A study combining Mendelian randomization and bioinformatics. [PDF]
J Alzheimers Dis RepBackground The association between gut microbes and Alzheimer's disease (AD) has not been entirely elucidated. Objective We aimed to demonstrate the association between gut microbes and AD and to further investigate the pathogenesis of microbes with a ...
Liu JY, Tan CY, Luo L, Yin X.
europepmc +2 more sources
mBio, 2017 Bacteria regulate chromosome replication and segregation tightly with cell division to ensure faithful segregation of DNA to daughter generations. The underlying mechanisms have been addressed in several model species.
Kati Böhm +5 more
doaj +2 more sources
The intrahepatic bacterial metataxonomic signature of patients with hepatocellular carcinoma. [PDF]
Sci RepDysbiosis of the gut-liver axis increases the risk of bacterial and metabolite influx into the liver, which may contribute to the development of hepatocellular carcinoma (HCC). In this study, we compared the microbiomes in HCC tumors and adjacent tissues.
Li J +5 more
europepmc +2 more sources