Metabolites, 2022 Anti-virulence agents are non-bacteriostatic and non-bactericidal emerging therapeutic options which hamper the production of virulence factors in pathogenic flora.
Yasuhiro Igarashi +2 more
exaly +4 more sources
F420H2-dependent degradation of aflatoxin and other furanocoumarins is widespread throughout the actinomycetales. [PDF]
PLoS ONE, 2012 Two classes of F(420)-dependent reductases (FDR-A and FDR-B) that can reduce aflatoxins and thereby degrade them have previously been isolated from Mycobacterium smegmatis. One class, the FDR-A enzymes, has up to 100 times more activity than the other. F(
Gauri V Lapalikar +5 more
doaj +2 more sources
A phylogenomic analysis of the
BMC Genomics, 2007 Background The genome of Mycobacterium tuberculosis harbors four copies of a cluster of genes termed mce operons. Despite extensive research that has demonstrated the importance of these operons on infection outcome, their physiological function remains ...
Riley Lee W, Casali Nicola
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Bioactivities and Extract Dereplication of Actinomycetales Isolated From Marine Sponges [PDF]
Frontiers in Microbiology, 2019 In the beginning of the twenty-first century, humanity faces great challenges regarding diseases and health-related quality of life. A drastic rise in bacterial antibiotic resistance, in the number of cancer patients, in the obesity epidemics and in ...
José D. Santos +15 more
doaj +6 more sources
Is the lower atmosphere a readily accessible reservoir of culturable, antimicrobial compound-producing Actinomycetales? [PDF]
Frontiers in Microbiology, 2015 Recent metagenomic studies have revealed that microbial diversity in the atmosphere rivals that of surface environments. This indicates that the atmosphere may be worth bioprospecting in for novel microorganisms, especially those selected for by harsh ...
Carolyn F. Weber, Jason T Werth
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Gut microbiota may affect Alzheimer's disease through synaptic function mediated by CAMs pathway: A study combining Mendelian randomization and bioinformatics [PDF]
Journal of Alzheimer's Disease ReportsBackground The association between gut microbes and Alzheimer's disease (AD) has not been entirely elucidated. Objective We aimed to demonstrate the association between gut microbes and AD and to further investigate the pathogenesis of microbes with a ...
Ji-yun Liu +3 more
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Journal of Mathematical and Fundamental Sciences, 2019 Ringkasan. Genus Micromonospora termasuk salahsatu genera dari Actinomycetales yang kurang dikenal. Kehidupannya umum secara mesofilik dan termofilik, dan ditemukan di dalam tanah, air, pupuk-kandang dan kompos.
U. Suriawiria
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The intrahepatic bacterial metataxonomic signature of patients with hepatocellular carcinoma [PDF]
Scientific ReportsDysbiosis of the gut-liver axis increases the risk of bacterial and metabolite influx into the liver, which may contribute to the development of hepatocellular carcinoma (HCC). In this study, we compared the microbiomes in HCC tumors and adjacent tissues.
Jie Li +5 more
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Association between gut microbiota and gastric cancers: a two-sample Mendelian randomization study [PDF]
Frontiers in MicrobiologyBackgroundGastric cancer (GC) is the fifth most commonly diagnosed cancer worldwide, with its etiology attributed to a complex interplay of genetic, dietary, environmental factors, and infections such as Helicobacter pylori.
Yuan Chang +2 more
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The Beneficial Effects of Actinomycetales Immune Modulators in the Pancreas of Diabetic Rats [PDF]
Advanced Pharmaceutical Bulletin, 2021 Purpose: Type 1 diabetes mellitus (T1DM) has dramatically increased in recent years, especially in young people, and limits the life quality of the patients involved.
Monireh Khordadmehr +6 more
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