Results 151 to 160 of about 55,270,452 (301)

Action Research for Sustainable Development in a Turbulent World: Reflections and Future Perspectives

, 2013
The purpose of this article is to reflect on a panel discussion about an edited book launched at the 2012 ALARA Conference in Sydney. The majority of authors participated in the launch discussion and presented the message of their chapters, exploring ...
Dick, Bob, Wood, Lesley, Zuber-Skerritt, Ortrun   +2 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Implementing palliative reasoning in multiprofessional palliative care: A participatory action research in the Netherlands. [PDF]

PLoS One
Kochems K, Teunissen SCCM, Hesselmann GM, Verkammen M, Uyttewaal G, Kalthoff K, de Graeff A, de Graaf E.   +7 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Optimization and Implementation of a Primary Care Nurse Training Program Using an Action Research Framework. [PDF]

J Multidiscip Healthc
Lin JY, Gong QQ, Chen YS, Xiang WT, Huang YT, Luo CL.   +5 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Tracing the development of primary students' expressed sustainability conceptions through SDG-based classroom action research. [PDF]

Front Psychol
Erbaş AA, Topcubaşı T.
europepmc   +1 more source

Education for sustainability: teachers conceptualize their new role by participatory action research

, 2017
Education for sustainability calls for a change in the frame of reference towards the world and therefore a profound change of the conventional education approach is required. This article presents a process of change in teachers' paradigmatic conception
Avriel-Avni, Noa
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Development and Usability Assessment of a Health Education Conversational Agent for Patients With Gastric Cancer: Action Research Study. [PDF]

J Med Internet Res
Kang Y, Yan Y, Wang T, Yu Z, Hu Y, Wang Z, Zhang J, Latour JM, Zhang Y.   +8 more
europepmc   +1 more source