Results 111 to 120 of about 13,692,662 (328)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Identifying Phlorofucofuroeckol-A as a Dual Inhibitor of Amyloid-β25-35 Self-Aggregation and Insulin Glycation: Elucidation of the Molecular Mechanism of Action [PDF]
Su Hui Seong +3 more
openalex +1 more source
Transcendental Method in Action [PDF]
Lonergan’s treatment of transcendental method in the first chapter of \u3cMethod in Theology\u3e presents a bit of a puzzle. Something about heightening consciousness at the level of experience is different from the reflexive operations by which we ...
Daly, Patrick
core
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Ensuring the rights of climate-displaced people in Bangladesh
Five critical areas require urgent action with the threat of internal displacement as a result of climate change already severe and growing in Bangladesh.
Prabal Barua +4 more
doaj
Comparison of Aliskiren/Hydrochlorothiazide Combination Therapy With Hydrochlorothiazide Monotherapy in Older Patients With Stage 2 Systolic Hypertension: Results of the ACTION Study [PDF]
Jan Basile +5 more
openalex +1 more source
Fractional Einstein-Hilbert Action Cosmology
We propose a new type of cosmological model derived from the fractional variational principle when it is applied to the gravitational sector of action functional.
Shchigolev, V. K.
core +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Background Minimum dietary diversity (MDD) is associated with malnutrition, influencing children’s growth and development. Understanding the relationship between maternal and child MDD is crucial as mothers play a central role in food preparation and ...
Melinda Mastan +5 more
doaj +1 more source

