Results 111 to 120 of about 5,887,355 (268)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Balance the scales of Technology Justice
, 2016 Animated infographic from Technology Justice: A Call to ActionInfographic encouraging action to achieve Technology Justice.
Practical Action
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, 2020 This case study used action learning and action research to examine the ways that the Shared Services Support Program (SSSP) could enhance the primary science mission on a federal research campus. This included the investigation into the role that social
Sigle, Christopher, Tetteh, Emmanuel
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Engaging the practice of Indigenous yarning in Action Research
, 2011 This paper discusses the technique of ‘yarning’ as an action research process relevant for policy development work with Aboriginal peoples. Through a case study of an Aboriginal community-based smoking project in the Australian State of Victoria, the ...
Fredericks, Bronywn, Adams, Karen
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
BMC ProceedingsThe 5th Preeclampsia Scientific Symposium (PSS2023) organized by Action on Preeclampsia (APEC) Ghana was themed: ‘Realign, Refocus: Improving outcomes of Hypertensive Disorders of Pregnancy through Shared Decision Making, Research & Quality of Care’.
Koiwah Koi-Larbi +6 more
doaj +1 more source
The generative and catalytic powers of creative, expressive arts in action research
, 2014 Being conscious of how we know what we know, and equally conscious that when we come to such an insight that our ways of knowing are not necessarily the same as everyone else’s, are increasingly essential aspects of methodological literacy.
Goff, Susan
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Maternal and Child NutritionSevere acute malnutrition (SAM) affects 12.2 million children globally. Integrating a water, sanitation and hygiene (WASH) kit in outpatient SAM treatment can improve recovery rates by preventing WASH‐related diseases and complications, but its cost at ...
Bibata Wassonguema +11 more
doaj +1 more source