Results 141 to 150 of about 13,692,662 (328)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Implementing a pragmatic randomised controlled trial in a humanitarian setting: lessons learned from the TISA trial

Trials
Introduction High-quality evidence is crucial for guiding effective humanitarian responses, yet conducting rigorous research, particularly randomised controlled trials, in humanitarian crises remains challenging.
D. S. N’Diaye, S. Frison, M. Ba, M. L. Lê, A. E. Cabo, F. Siroma, A. Devort, C. MacLeod, J. Lapègue, M. Seye, A. B. Traoré, T. Cerveau, D. Léger, K. Gallandat, Y. Gnokane, A. Vargas Brizuela, S. Stern, L. Braun, O. Cumming   +18 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Men’s collective action willingness: Testing different theoretical models of protesting gender inequality for women and men.

, 2016
Andrew L. Stewart
openalex   +1 more source

Minimum orbit dimension for local unitary action on n-qubit pure states [PDF]

, 2005
David W. Lyons, Scott N. Walck
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Changing minds about climate change in Indonesia through a TV drama

Frontiers in Communication
Drama has been shown to change attitudes and inspire action on topics as diverse as health, sanitation, intergroup conflict, and gender equality, but rarely have randomized trials assessed the influence of narrative entertainment programs focusing on ...
Donald P. Green, Rosiana Eko, Lionel Ong, Lionel Ong, Benedek Paskuj, Anna Godfrey, Ankur Garg, Helena Rea   +7 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Conditional Action and Quantum Versions of Maxwell’s Demon

, 2020
Heinz-Jürgen Schmidt
openalex   +1 more source

Norm as an exclusionary reason for action [PDF]

, 2021
Hadži Stević Brano
openalex   +1 more source