RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Rethinking the Origins of Cross-Language Effects: How Heard Verbs Influence Japanese- and English-Speaking Children's Attention to the Details of Actions. [PDF]
Hagihara H +3 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Bindings for Action: Bridging the Gap Between Theories of Procedural Working Memory and Action Control Research. [PDF]
Frischkorn GT +7 more
europepmc +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Co-Creating a Digital Learning Platform for Cross-Sectoral Virtual Consultations: An Action Research Study. [PDF]
Bagger B +4 more
europepmc +1 more source
The AMR footprint: an integrative indicator in the global response to antimicrobial resistance. [PDF]
Essack SY.
europepmc +1 more source
Integrating contrastive cross-modal attention and stacked GRU for hand function rehabilitation robot control. [PDF]
Liu W, Wu H, Feng SF, Luo CL.
europepmc +1 more source

