Results 61 to 70 of about 5,887,355 (268)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

So you think you are doing action research? Indicators of enactment of participatory action research in higher education

, 2013
Action Research is being adopted as a research and project method for the higher education learning and teaching sector. A researcher new to Action Research may need to be scaffolded through the process of validating their research as Action Research ...
Harvey, Marina
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Peer assisted teaching scheme and Participative Action Learning Action Research: A winning combination

, 2015
This paper demonstrates synergetic influences of systems thinking upon a third cycle of action research aimed at improve teaching skills and the student experience.
Cameron, Leone Carol
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Walking a tightrope: perspectives of non-degree allopathic providers (NDAPs) on providing diabetes and hypertension care in urban informal settlements of Mumbai Metropolitan Region

BMC Health Services Research
Background In India, Non-Degree Allopathic Providers (NDAPs), who do not have formal training in allopathic medicine, play a prominent role in basic healthcare delivery in both rural areas and urban informal settlements. Often recognized as providers of ‘
Manjula Bahuguna, Jennifer Spencer, Sudha Ramani, Sweety Pathak, Sushma Shende, Shanti Pantvaidya, Vanessa D’Souza, Anuja Jayaraman   +7 more
doaj   +1 more source

Costs and cost-efficiency of a mobile cash transfer to prevent child undernutrition during the lean season in Burkina Faso: a mixed methods analysis from the MAM’Out randomized controlled trial

Cost Effectiveness and Resource Allocation, 2018
Background This study assessed the costs and cost-efficiency of a mobile cash transfer implemented in Tapoa Province, Burkina Faso in the MAM’Out randomized controlled trial from June 2013 to December 2014, using mixed methods and taking a societal ...
Chloe Puett, Cécile Salpéteur, Freddy Houngbe, Karen Martínez, Dieynaba S. N’Diaye, Audrey Tonguet-Papucci   +5 more
doaj   +1 more source

Communal-Photosynthesis Metaphor: Autobiographical Action-Research Journeys and Heuristic-Action-Learning Frameworks of Living Educational Theories

, 2015
This article provides a creative analysis of reflective thought processes grounded in the systemic thinking of an autobiographical account of action-research journeys from the context of action-learning experiences that led to the discovery of the ...
Tetteh, Emmanuel Nii Ayikwei
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Incidence and antimicrobial resistance of non-typhoidal Salmonella enterica in stool samples from children under five in peri-urban Ouagadougou, Burkina Faso

BMC Microbiology
Background Non-typhoidal Salmonella (NTS) causes significant illness worldwide, particularly in sub-Saharan Africa. Poor sanitation, limited healthcare, and rising antimicrobial resistance (AMR) worsen its impact on children under five.
Alimatou Héma, Ben I. Soulama, Jean Sawadogo, Amidou Z. Ouédraogo, Denise Hien, Issa Nébié, Sophie Houard, Alphonse Ouédraogo, Alfred B. Tiono, Mahamoudou Sanou, Sodiomon B. Sirima   +10 more
doaj   +1 more source