Results 71 to 80 of about 1,690,454 (303)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Temporary use & collective action

open access: yesPlaNext, 2018
Amongst the proliferation of practice- and theory-based concepts that are changing urban planning, the renaissance of resilience is proving its potential for impressive implications instead of remaining a brief trend.
Robin A. Chang
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Multidimensionally-constrained relativistic mean-field study of spontaneous fission: coupling between shape and pairing degrees of freedom

open access: yes, 2016
Studies of fission dynamics, based on nuclear energy density functionals, have shown that the coupling between shape and pairing degrees of freedom has a pronounced effect on the nonperturbative collective inertia and, therefore, on dynamic (least-action)
Lu, Bing-Nan   +4 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

L’acteur civil entre l’ultime action associative et l’ultime engagement politique : étude de cas de la ville de Midelt au Maroc

open access: yesM@GM@, 2023
À travers ce travail, nous avons tenté dans un contexte local qui est la ville de Midelt d’étudier la relation, les différences et les points communs entre le corps de la société civile et celui des partis politiques, d’éclairer les limites entre un ...
Youssef Alaoui
doaj  

Collective action in space: assessing how collective action varies across an African landscape [PDF]

open access: yes
This paper develops and applies a new approach for analyzing the spatial aspects of individual adoption of a technology that produces a mixed public-private good.
McCarthy, Nancy   +4 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMPLEX COLLECTIVE DUTIES & ACTION-GUIDANCE

open access: yesKriterion
We can often find in the literature (both popular and academic) ascriptions of complex collective duties to extensive unstructured collections of individuals.
Cristian Rettig
doaj   +1 more source

Gender and collective action: A conceptual framework for analysis [PDF]

open access: yes
"This paper presents a framework for investigating the intersection of collective action and gender; i.e. how gender-oriented analysis can foster more effective collective action in the context of agriculture and natural resource management and how ...
Dohrn, Stephan   +2 more
core  

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