Results 111 to 120 of about 6,733,413 (292)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of all healthcare professionals in cessation
Jazmin Devonish +5 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Coffee berry borer triple-action integrated pest management [PDF]
In coffee plantations, some of the coffee berry borer (#Hypothenemus hampei Ferrari#) females emerging from residual fruits survive by taking refuge in dry fruits remaining on the branches.
Dufour, Bernard Pierre
core
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
As Time Goes By: Event File Decay Does Not Unleash Inhibition of Return
Inhibition of return (IOR) refers to a location repetition cost typically observed when signaling the detection of or localizing sequentially presented stimuli repeating or changing their location.
Lars-Michael Schöpper, Christian Frings
doaj +1 more source
Mobile technology is regarded as a helpful tool facilitating language learning. However, the success of mobile technology largely depends on learners’ acceptance.
Hui-Tzu Hsu, Chih-Cheng Lin
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Effort and the Standard Story of Action [PDF]
In this paper, I present an alternative account of action that improves upon what has come to be known as the standard story. The standard story depicts actions as events that are caused by and made intelligible through the appropriate combinations of ...
Brent, Michael
core

