Results 181 to 190 of about 30,938 (292)

Synthesis of Pyrido[2,3‐d]Azolopyrimidinones: Design and Epidermal Growth Factor Receptor‐Targeted Molecular Docking Toward Novel Anticancer Leads

open access: yesChemistryOpen, EarlyView.
New pyrido[2,3‐d]azolopyrimidinones were synthesized and evaluated as potent EGFR‐targeted anticancer leads. Molecular docking and cytotoxicity studies revealed strong receptor binding and submicromolar activity, highlighting this scaffold as a promising framework for future targeted drug development.
Sobhi M. Gomha   +6 more
wiley   +1 more source

2,3‐Dichloro‐5,6‐Dicyano‐1,4‐Benzoquinone (DDQ)‐Mediated CC Bond Formation: Redox Strategies from Stoichiometric to Catalytic Systems

open access: yesChemistryOpen, EarlyView.
2,3‐Dichloro‐5,6‐dicyano‐1,4‐benzoquinone serves as a versatile oxidant and redox catalyst for CC bond formation through hydride abstraction or single‐electron transfer. Stoichiometric and catalytic systems enable benzylic, allylic, and aromatic CH activation under mild, metal‐free conditions, providing sustainable routes to complex and bioactive ...
Dohoon Cha, Sun‐Joon Min
wiley   +1 more source

Populism and policy capacity: Evidence from an opposition municipality in Istanbul

open access: yesPublic Administration and Development, EarlyView.
Abstract Despite achievements in its conceptual rigor, policy capacity still represents a relatively depoliticized concept that fails to sufficiently consider the ways in which politics plays a role in its creation, mobilization, or decay. This article seeks to contribute to this debate by investigating the impact of populism on policy capacity, the ...
Ebru Ertugal, Faik Gür, İnan Sevinç
wiley   +1 more source

Mitigating Health Disparities Through Empathetic Policymaking During Times of Crisis

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT The COVID‐19 pandemic greatly exacerbated the existing disparities and inequities in health and healthcare among historically marginalized populations. Today, these impacts still echo. These persistent structured inequities erode the public's trust in government, lead to failure in public policies, and result in worse health consequences ...
Yali Pang   +2 more
wiley   +1 more source

A green solvent processable, self‐doped N‐annulated perylene butyl tetraester applied as a solar cell cathode interlayer

open access: yesPolymer International, EarlyView.
A new organic molecular cathode interlayer is presented built upon the perylene butyl tetraester scaffold. The new molecule incorporates N‐annulation and a functional amine group to control optical, electrochemical and physical properties and delivers excellent solar cell performance. Abstract We report a new amino‐bay‐substituted, N‐annulated perylene
Kathryn M Wolfe   +7 more
wiley   +1 more source

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