Results 101 to 110 of about 3,163,690 (243)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Researching resilience in action: Matters of action research as ‘matters of care’

open access: yes, 2022
This paper traces my Action Research (AR) journey and suggests a care perspective to AR. In my research that investigated the idea of resilience in disaster recovery, I engaged in a five-year collaborative inquiry of what it means to do resilience with a
Mikami, Akina
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Jack the lion – the making of a film about action research as action research

open access: yes, 2020
In the pages that follow, it will be argued that the process of action research and the production of a documentary film are structurally comparable. Based on this assumption, this text tells the story of the making of a film on action research.
Har-Gil, Amir, Rauch, Franz
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Peer assisted teaching scheme and Participative Action Learning Action Research: A winning combination

open access: yes, 2015
This paper demonstrates synergetic influences of systems thinking upon a third cycle of action research aimed at improve teaching skills and the student experience.
Cameron, Leone Carol
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Communal-Photosynthesis Metaphor: Autobiographical Action-Research Journeys and Heuristic-Action-Learning Frameworks of Living Educational Theories

open access: yes, 2015
This article provides a creative analysis of reflective thought processes grounded in the systemic thinking of an autobiographical account of action-research journeys from the context of action-learning experiences that led to the discovery of the ...
Tetteh, Emmanuel Nii Ayikwei
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Keynote address: The action learning, action research experiences of professionals

open access: yes, 2019
This keynote relates the experiences of professional educational-practitioners, which contribute to the legacy of action learners, action researchers, and others concerned with transforming social change for the flourishing of humanity.
Whitehead, Jack
core  

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