Results 121 to 130 of about 877,795 (308)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Action preparation helps and hinders perception of action [PDF]
, 2010 Several theories of the mechanisms linking perception and action require that the links are bidirectional, but there is a lack of consensus on the effects that action has on perception.
Eimer, M +17 more
core +1 more source
Frontiers in Human Neuroscience, 2019 Walking plays an important role in human daily life. Many previous studies suggested that long-term walking training can modulate brain functions. However, due to the use of measuring techniques such as fMRI and PET, which are highly motion-sensitive, it
Qihan Zhang +16 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Joint action and development [PDF]
, 2011 Given the premise that joint action plays some role in explaining how humans come to understand minds, what could joint action be? Not what a leading account, Michael Bratman’s, says it is. For on that account engaging in joint action involves sharing
Butterfill, Stephen A. (Stephen Andrew) +1 more
core +1 more source
Frontiers in Human Neuroscience, 2018 Studying brain mechanisms underlying the prediction of observed action, the dorsal premotor cortex (PMd) has been suggested a key area. The present study probed this notion using repetitive transcranial magnetic stimulation (rTMS) to test whether ...
Louisa F. M. Brich +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Effects of action observation on learning non-weight-bearing gait with crutches
Cogent Psychology, 2018 Action observation (AO) has been used to improve rehabilitation outcomes. We examined the effects of AO gait training on the acquisition of a non-weight-bearing (NWB) gait with crutches.
Hiroshi Osaka +4 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Interhemispheric inhibition is dynamically regulated during action observation [PDF]
, 2016 International audienceIt is now well established that the motor system plays a pivotal role in action observation and that the neurophysiological processes underlying perception and action overlaps.
Papaxanthis, Charalambos +3 more
core +1 more source