Results 241 to 250 of about 3,126,670 (274)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Sensitivity and specificity of the action observation network to kinematics, target object, and gesture meaning. [PDF]

Hum Brain Mapp
Simonelli F, Handjaras G, Benuzzi F, Bernardi G, Leo A, Duzzi D, Cecchetti L, Nichelli PF, Porro CA, Pietrini P, Ricciardi E, Lui F.   +11 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

The Effects of Action Observation Speed on Motor Function in Patients with Chronic Low Back Pain: From Observation to Execution. [PDF]

Brain Sci
Grande-Alonso M, Estradera-Bel M, Forner-Álvarez C, Cuenca-Martínez F, Vidal-Quevedo C, Paris-Alemany A, La Touche R.   +6 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Effect of gender matching and attentional focus on the link between action observation and action verb processing. [PDF]

Sci Rep
Francisco V, Valentin M, Decatoire A, Bidet-Ildei C.   +3 more
europepmc   +1 more source

Efficacy of a Rehabilitation Treatment Using Action Observation Therapy Enhanced by Muscle Synergy-Derived Electrical Stimulation (OTHELLO) in Post-Stroke Patients: A RCT Study Protocol. [PDF]

J Cent Nerv Syst Dis
Cabinio M, Lencioni T, Nuara A, Rossetto F, Blasi V, Bailo G, Cardini R, Bertoni R, Viganò A, Bianco M, Comanducci A, Avanzini P, Ferrarin M, Fornia L, Baglio F.   +14 more
europepmc   +1 more source

Action Observation and Motor Imagery as a Treatment in Patients with Parkinson's Disease. [PDF]

J Parkinsons Dis
Mezzarobba S, Bonassi G, Avanzino L, Pelosin E.   +3 more
europepmc   +1 more source

Stimulus specificity in combined action observation and motor imagery of typing. [PDF]

Q J Exp Psychol (Hove)
Woodrow-Hill C, Gowen E, Vogt S, Edmonds E, Poliakoff E.   +4 more
europepmc   +1 more source

The Acute Effects of Motor Imagery Combined With Action Observation Breathing Exercise on Cardiorespiratory Responses, Brain Activity, and Cognition: A Randomized, Controlled Trial. [PDF]

Cardiovasc Ther
Atak E, Ataç A.
europepmc   +1 more source